Semi-automatic medical image segmentation with adaptive local statistics in Conditional Random Fields framework Conference Paper


Authors: Hu, Y. C.; Grossberg, M. D.; Mageras, G. S.
Title: Semi-automatic medical image segmentation with adaptive local statistics in Conditional Random Fields framework
Conference Title: 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Abstract: Planning radiotherapy and surgical procedures usually require onerous manual segmentation of anatomical structures from medical images. In this paper we present a semi-automatic and accurate segmentation method to dramatically reduce the time and effort required of expert users. This is accomplished by giving a user an intuitive graphical interface to indicate samples of target and non-target tissue by loosely drawing a few brush strokes on the image. We use these brush strokes to provide the statistical input for a Conditional Random Field (CRF) based segmentation. Since we extract purely statistical information from the user input, we eliminate the need of assumptions on boundary contrast previously used by many other methods, A new feature of our method is that the statistics on one image can be reused on related images without registration. To demonstrate this, we show that boundary statistics provided on a few 2D slices of volumetric medical data, can be propagated through the entire 3D stack of images without using the geometric correspondence between images. In addition, the image segmentation from the CRF can be formulated as a minimum s-t graph cut problem which has a solution that is both globally optimal and fast. The combination of a fast segmentation and minimal user input that is reusable, make this a powerful technique for the segmentation of medical images.
Keywords: methodology; reproducibility; reproducibility of results; computer assisted tomography; classification; statistics; tomography, x-ray computed; pathology; diagnostic imaging; algorithms; automation; liver; algorithm; probability; models, statistical; image quality; phantoms, imaging; image processing, computer-assisted; image processing; computer program; computer graphics; software; statistical model; normal distribution
Journal Title IEEE Engineering in Medicine and Biology Society. Conference Proceedings
Volume: 2008
Conference Dates: 2008 Aug 20-25
Conference Location: Vancouver, Canada
ISBN: 1557-170X
Publisher: IEEE  
Date Published: 2008-01-01
Start Page: 3099
End Page: 3102
Language: English
PUBMED: 19163362
PROVIDER: scopus
PMCID: PMC2882883
DOI: 10.1109/IEMBS.2008.4649859
DOI/URL:
Notes: --- - "Export Date: 17 November 2011" - "Source: Scopus"
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MSK Authors
  1. Gikas S Mageras
    277 Mageras
  2. Yu-Chi Hu
    118 Hu
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