A model-aided segmentation in urethra identification based on an atlas human autopsy image for intensity modulated radiation therapy Conference Paper


Authors: Song, Y.; Muller, B.; Burman, C.; Mychalczak, B.
Title: A model-aided segmentation in urethra identification based on an atlas human autopsy image for intensity modulated radiation therapy
Conference Title: 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
Abstract: In order to protect urethra in radiation therapy of prostate cancer, the urethra must be identified and localized as an organ at risk (OAR) for the inverse treatment planning in intensity modulated radiation therapy (IMRT). Because the prostatic urethra and its surrounding prostate tissue have similar physical characteristics, such as linear attenuation coefficient and density, it is difficult to distinct the OAR from the target in CT images. To localize the urethra without using contrast agent or additional imaging modalities other than planning CT images, a different approach was developed using a standard atlas of human anatomy image. This paper reports an investigation, in which an adult urethra was modeled based on a human anatomic image. An elastic model was build to account for a uniform tissue deformation of the prostate. This model was then applied to patients to localize their urethras and preliminary results are presented. ©2007 IEEE.
Keywords: image analysis; radiotherapy; oncology; computerized tomography; tumors; image segmentation; health risks; mathematical models; intensity modulated radiation therapy (imrt); linear attenuation coefficients
Journal Title IEEE Engineering in Medicine and Biology Society. Conference Proceedings
Conference Dates: 2007 Aug 23-26
Conference Location: Lyon, France
ISBN: 1557-170X
Publisher: IEEE  
Date Published: 2007-01-01
Start Page: 3532
End Page: 3535
Language: English
DOI: 10.1109/IEMBS.2007.4353093
PROVIDER: scopus
DOI/URL:
Notes: --- - "PMID:18002759" - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings - Annu Int Conf IEEE Eng Med Biol Proc - "Conference code: 70818" - "Export Date: 17 November 2011" - "Art. No.: 4353093" - "CODEN: CEMBA" - "Sponsors: ACIES, Research Promotion and Management Consulting; EOARD, European Office of Aerospace R and D; Grand Lyon; NSF, National Science Foundation; Philips Research Europe; Philips Research North America" - 23 August 2007 through 26 August 2007 - "Source: Scopus"
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