From intensity modulated radiation therapy to 4D radiation therapy - An advance in targeting mobile lung tumors Conference Paper
| Authors: | Song, Y.; Muller, B.; Burman, C.; Mychalczak, B. |
| Title: | From intensity modulated radiation therapy to 4D radiation therapy - An advance in targeting mobile lung tumors |
| Conference Title: | 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07 |
| Abstract: | Intensity modulated radiation therapy (IMRT) has been widely used in the treatment of lung cancer. The highly conformal dose distribution with steep gradients could miss the target if respiratory motion is not carefully considered during the treatment planning. The issue becomes particularly critical when dose escalation technique is used. To account for this periodical respiratory motion, the common practice is to add an empirical population-based safety margin to the clinical target volume (CTV). However, such a uniform margin does not reflect the fact that respiratory motion is not isotropic. In addition, it is not tailored to each individual patient. Thus, it is not optimal in both tumor targeting and normal tissue sparing. Here, we present our approach to 4D radiation therapy using the Bellows tracking system for targeting mobile lung tumors. The objective was to develop a clinically viable procedure for routine 4D treatment planning. © 2007 IEEE. |
| Keywords: | treatment planning; radiotherapy; tumors; dosimetry; respiratory motion; pulmonary diseases |
| Journal Title | IEEE Engineering in Medicine and Biology Society. Conference Proceedings |
| Conference Dates: | 2007 Aug 23-26 |
| Conference Location: | Lyon, France |
| ISBN: | 1557-170X |
| Publisher: | IEEE |
| Date Published: | 2007-01-01 |
| Start Page: | 226 |
| End Page: | 229 |
| Language: | English |
| DOI: | 10.1109/IEMBS.2007.4352264 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings - Annu Int Conf IEEE Eng Med Biol Proc - "Conference code: 70818" - "Cited By (since 1996): 1" - "Export Date: 17 November 2011" - "Article No. 4352264" - "CODEN: CEMBA" - "Sponsors: ACIES, Research Promotion and Management Consulting; EOARD, European Office of Aerospace R and D; Grand Lyon; NSF, National Science Foundation; Philips Research Europe; Philips Research North America" - 23 August 2007 through 26 August 2007 - "Source: Scopus" |
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116Song
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