Comparison of two methods for assessing erectile function before radical prostatectomy Research Letter


Authors: Bravi, C. A.; Tin, A.; Benfante, N.; Salonia, A.; Briganti, A.; Montorsi, F.; Mulhall, J. P.; Eastham, J. A.; Vickers, A. J.
Title: Comparison of two methods for assessing erectile function before radical prostatectomy
Abstract: Patient-reported outcome instruments for erectile function often ask respondents about their experience over the previous 4 wk. This is problematic for baseline assessment of patients with prostate cancer (PC) before treatment, as the previous 4 wk would probably have involved procedures such as biopsy and considerable anxiety related to their diagnosis. At San Raffaele Hospital, the International Index of Erectile Function (IIEF-6) was used to ask new PC patients about function in both the previous 4 wk and 6 mo. We compared responses to these two timeframes. IIEF-6 scores were lower for the 4-wk period (median 24 vs 26; p < 0.0001) predominately because approximately one in six of patients with good function in the 6-mo time frame had very poor function in the 4 wk before completing the questionnaire (adequate erectile function 60% and 51%; absolute difference 9%, 95% confidence interval 8-10%). Results were further confirmed using a comparison group of 5395 patients with PC newly diagnosed at Memorial Sloan Kettering Cancer Center who had similar function in the previous 6 mo. Erectile function evaluation for men presenting with PC should involve asking about typical function over a 6-mo period rather than focusing on the previous 4 wk. Patient summary: Questionnaires to assess erectile function often ask men about function in the previous 4 wk. We found that this underestimates function in new prostate cancer patients and that such men should be asked about typical function over a 6-mo period. (c) 2019 European Association of Urology. Published by Elsevier B.V. All rights reserved.
Keywords: radical prostatectomy; patient-reported outcomes; erectile dysfunction; international index; iief questionnaire
Journal Title: European Urology Oncology
Volume: 4
Issue: 2
ISSN: 2588-9311
Publisher: Elsevier BV  
Date Published: 2021-04-01
Start Page: 323
End Page: 326
Language: English
ACCESSION: WOS:000640189300026
DOI: 10.1016/j.euo.2019.02.003
PROVIDER: wos
PUBMED: 31412005
Notes: Article -- Source: Wos
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MSK Authors
  1. John P Mulhall
    603 Mulhall
  2. Andrew J Vickers
    887 Vickers
  3. James Eastham
    540 Eastham
  4. Nicole E Benfante
    161 Benfante
  5. Amy Lam Ling Tin
    116 Tin
  6. Carlo Andrea Bravi
    9 Bravi