Abstract: |
Patient-reported outcome instruments for erectile function often ask respondents about their experience over the previous 4 wk. This is problematic for baseline assessment of patients with prostate cancer (PC) before treatment, as the previous 4 wk would probably have involved procedures such as biopsy and considerable anxiety related to their diagnosis. At San Raffaele Hospital, the International Index of Erectile Function (IIEF-6) was used to ask new PC patients about function in both the previous 4 wk and 6 mo. We compared responses to these two timeframes. IIEF-6 scores were lower for the 4-wk period (median 24 vs 26; p < 0.0001) predominately because approximately one in six of patients with good function in the 6-mo time frame had very poor function in the 4 wk before completing the questionnaire (adequate erectile function 60% and 51%; absolute difference 9%, 95% confidence interval 8-10%). Results were further confirmed using a comparison group of 5395 patients with PC newly diagnosed at Memorial Sloan Kettering Cancer Center who had similar function in the previous 6 mo. Erectile function evaluation for men presenting with PC should involve asking about typical function over a 6-mo period rather than focusing on the previous 4 wk. Patient summary: Questionnaires to assess erectile function often ask men about function in the previous 4 wk. We found that this underestimates function in new prostate cancer patients and that such men should be asked about typical function over a 6-mo period. (c) 2019 European Association of Urology. Published by Elsevier B.V. All rights reserved. |