Natural killer cells: From innate to adaptive features Review
| Authors: | Mujal, A. M.; Delconte, R. B.; Sun, J. C. |
| Review Title: | Natural killer cells: From innate to adaptive features |
| Abstract: | Natural killer (NK) cells are innate lymphocytes that provide critical host defense against pathogens and cancer. Originally heralded for their early and rapid effector activity, NK cells have been recognized over the last decade for their ability to undergo adaptive immune processes, including antigen-driven clonal expansion and generation of long-lived memory. This review presents an overview of how NK cells lithely partake in both innate and adaptive responses and how this versatility is manifest in human NK cell-mediated immunity. © 2021 Annual Reviews Inc.. All rights reserved. |
| Keywords: | innate immunity; immunological memory; human cytomegalovirus; mcmv; mouse cytomegalovirus; hcmv; adaptive nk cell |
| Journal Title: | Annual Review of Immunology |
| Volume: | 39 |
| ISSN: | 0732-0582 |
| Publisher: | Annual Reviews |
| Date Published: | 2021-04-01 |
| Start Page: | 417 |
| End Page: | 447 |
| Language: | English |
| DOI: | 10.1146/annurev-immunol-101819-074948 |
| PUBMED: | 33902312 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Export Date: 1 June 2021 -- Source: Scopus |
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