Multispectral imaging for metallic biopsy marker detection during MRI-guided breast biopsy: A feasibility study for clinical translation Journal Article
| Authors: | Eskreis-Winkler, S.; Simon, K.; Reichman, M.; Spincemaille, P.; Nguyen, T. D.; Christos, P. J.; Drotman, M.; Prince, M. R.; Pinker, K.; Sutton, E. J.; Morris, E. A.; Wang, Y. |
| Article Title: | Multispectral imaging for metallic biopsy marker detection during MRI-guided breast biopsy: A feasibility study for clinical translation |
| Abstract: | Purpose: To assess the feasibility and diagnostic accuracy of multispectral MRI (MSI) in the detection and localization of biopsy markers during MRI-guided breast biopsy. Methods: This prospective study included 20 patients undergoing MR-guided breast biopsy. In 10 patients (Group 1), MSI was acquired following tissue sampling and biopsy marker deployment. In the other 10 patients (Group 2), MSI was acquired following tissue sampling but before biopsy marker deployment (to simulate deployment failure). All patients received post-procedure mammograms. Group 1 and Group 2 designations, in combination with the post-procedure mammogram, served as the reference standard. The diagnostic performance of MSI for biopsy marker identification was independently evaluated by two readers using two-spectral-bin MR and one-spectral-bin MR. The κ statistic was used to assess inter-rater agreement for biopsy marker identification. Results: The sensitivity, specificity, and accuracy of biopsy marker detection for readers 1 and 2 using 2-bin MSI were 90.0% (9/10) and 90.0% (9/10), 100.0% (10/10) and 100.0% (10/10), 95.0% (19/20) and 95.0% (19/20); and using 1-bin MSI were 70.0% (7/10) and 80.0% (8/10), 100.0% (8/8) and 100.0% (10/10), 85.0% (17/20) and 90.0% (18/20). Positive predictive value was 100% for both readers for all numbers of bins. Inter-rater agreement was excellent: κ was 1.0 for 2-bin MSI and 0.81 for 1-bin MSI. Conclusion: MSI is a feasible, diagnostically accurate technique for identifying metallic biopsy markers during MRI-guided breast biopsy and may eliminate the need for a post-procedure mammogram. © Copyright © 2021 Eskreis-Winkler, Simon, Reichman, Spincemaille, Nguyen, Christos, Drotman, Prince, Pinker, Sutton, Morris and Wang. |
| Keywords: | mammography; multispectral imaging; biopsy marker; breast magnetic resonance imaging (mri); magnetic resonance imaging (mri)-guided breast biopsy |
| Journal Title: | Frontiers in Oncology |
| Volume: | 11 |
| ISSN: | 2234-943X |
| Publisher: | Frontiers Media S.A. |
| Date Published: | 2021-03-22 |
| Start Page: | 605014 |
| Language: | English |
| DOI: | 10.3389/fonc.2021.605014 |
| PROVIDER: | scopus |
| PMCID: | PMC8020905 |
| PUBMED: | 33828972 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 3 May 2021 -- Source: Scopus |
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