MRI-guided 9-gauge vacuum-assisted breast biopsy: Initial clinical experience Journal Article


Authors: Liberman, L.; Bracero, N.; Morris, E.; Thornton, C.; Dershaw, D. D.
Article Title: MRI-guided 9-gauge vacuum-assisted breast biopsy: Initial clinical experience
Abstract: OBJECTIVE. The objective of this study was to evaluate our initial clinical experience with MRI-guided vacuum-assisted breast biopsy as an alternative to surgical excision. MATERIALS AND METHODS. A retrospective review revealed 112 consecutive nonpalpable, mammographically occult MRI-detected breast lesions scheduled for MRI-guided vacuum-assisted biopsy. Biopsy was performed with a 9-gauge vacuum-assisted biopsy probe (Suros Surgical Systems) followed by clip placement (Artemis Medical). Medical records and histologic findings were reviewed. RESULTS. Among 112 lesions, biopsy was cancelled because of nonvisualization of the lesion in 14 (12%). Of the remaining 98 lesions, tissue was successfully acquired in 95 (97%). The median number of specimens obtained was 12 (range, 6-20). The median time to perform MRI-guided biopsy was 33 min for one lesion and 56 min for two lesions. Histology in 95 lesions was benign and concordant in 52 (55%), cancer in 24 (25%), high-risk in 10 (11%), and discordant in nine (9%). MRI-guided biopsy histologies in 24 cancers were ductal carcinoma in situ in 13 (54%) and infiltrating carcinoma in 11 (46%). Seven additional cancers were found at surgery in four discordant lesions and in three high-risk lesions. The clip successfully deployed in 86 (95%) of 91 lesions. Six complications (three hematomas, two instances in which the biopsy probe pierced the skin on the far side of the breast, and one vasovagal reaction) resolved without sequelae. CONCLUSION. MRI-guided vacuum-assisted biopsy is a fast and safe alternative to surgical biopsy for MRI-detected breast lesions. Imaging-histologic correlation is necessary to ensure lesion sampling. © American Roentgen Ray Society.
Keywords: middle aged; retrospective studies; histopathology; review; cancer risk; nuclear magnetic resonance imaging; follow up; methodology; magnetic resonance imaging; cancer diagnosis; treatment indication; diagnostic procedure; breast cancer; image analysis; breast; tumor biopsy; pathology; breast neoplasms; retrospective study; biopsy; high risk patient; time; time factors; mammography; instrumentation; breast tumor; carcinoma in situ; medical record; intermethod comparison; informed consent; hematoma; breast biopsy; breast lesion; vacuum; skin injury; surgical instruments; surgical instrument; vacuum extraction
Journal Title: American Journal of Roentgenology
Volume: 185
Issue: 1
ISSN: 0361-803X
Publisher: American Roentgen Ray Society  
Date Published: 2005-07-01
Start Page: 183
End Page: 193
Language: English
PROVIDER: scopus
PUBMED: 15972421
DOI/URL:
Notes: --- - "Cited By (since 1996): 74" - "Export Date: 24 October 2012" - "CODEN: AJROA" - "Source: Scopus"
Citation Impact
MSK Authors
  1. D David Dershaw
    223 Dershaw
  2. Laura Liberman
    176 Liberman
  3. Elizabeth A Morris
    341 Morris