Development and evaluation of stem cell collection procedure diagrams to support the education and recruitment of committed stem cell donors Journal Article


Authors: Fingrut, W.; Cuperfain, A. B.; Chan, S. W. S.; Ptak, E.; Kahlon, M.; Dhaliwal, J.; Naidu, A.; Wang, Y.; Baribeau, O.; Mahmoudi, T.; Lee, A.; Suppiah, R.; Luo, O. D.; Green, M.; Weiss, J. T.; Mercer, D.; Elmoazzen, H.; Petraszko, T.; Allan, D.
Article Title: Development and evaluation of stem cell collection procedure diagrams to support the education and recruitment of committed stem cell donors
Abstract: Background: Diagrams which allow potential unrelated stem cell donors to visualize the stem cell collection process were hypothesized to support the recruitment and education of committed stem cell donors. Study design and methods: A series of bone marrow and peripheral blood stem cell collection procedure diagrams were developed, featuring young adult male donors of varied ethnic backgrounds. Post-implementation, surveys were conducted to evaluate stakeholder perspective on the diagrams’ utility. A quality improvement project was conducted at five stem cell drives from 2017 to 2018 at which recruiters did or did not show the diagrams to potential donors. Following the drives, registrants were invited to complete a survey exploring their experience, knowledge and attitude towards donation. Results: The diagrams were implemented in Canada in 07/2016. Of 293 participating registrants (24·7% non-Caucasian males) recruited at five drives between 2017 and 2018, 76% (n = 197) were shown the diagrams. Participants who were shown the diagrams were significantly more likely to report that the recruiters appeared very knowledgeable (89% vs. 76%, P = 0·019) and to report improved self-reported knowledge of stem cell donation (P = 0·010) compared to participants not shown the diagram. Data are also shown demonstrating that stakeholders in donor recruitment used and valued the diagrams and that use of the diagrams was associated with improved donor recruitment outcomes in Canada. Conclusion: This report is the first evaluation of stem cell collection diagrams in the literature. The diagrams are relevant to donor registries, recruitment organizations and transplant centres worldwide, and their use may support efforts to educate and recruit committed, ethnically diverse donors. © 2020 International Society of Blood Transfusion
Keywords: adult; controlled study; young adult; human cell; major clinical study; bone marrow; donor; peripheral blood stem cell; education; total quality management; organization; attitude; bone marrow cell; informed consent; canada; human experiment; human; male; article; donation; donor recruitment
Journal Title: Vox Sanguinis
Volume: 116
Issue: 2
ISSN: 0042-9007
Publisher: Blackwell Publishing  
Date Published: 2021-02-01
Start Page: 239
End Page: 248
Language: English
DOI: 10.1111/vox.13010
PUBMED: 32970876
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 1 April 2021 -- Source: Scopus
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