Adjuvant chemotherapy for early-stage breast cancer Journal Article
| Authors: | Mcarthur, H. L.; Hudis, C. A. |
| Article Title: | Adjuvant chemotherapy for early-stage breast cancer |
| Abstract: | Systemic chemotherapy is an integral component of the adjuvant treatment strategy for women who have early-stage breast cancer and accounts for significant improvements in breast cancer-specific mortality. Decisions regarding adjuvant therapy are increasingly complex with the advent of new therapeutic strategies, a growing body of literature on the molecular biology and natural history of breast cancer, and advances in therapeutic techniques and early detection. Ultimately, the risk-benefit calculus will continue to evolve in response to these advances and one hopes that clinicians will soon be able to tailor treatment recommendations to the biology of an individual cancer and the needs of the affected individual. © 2007 Elsevier Inc. All rights reserved. |
| Keywords: | cancer survival; treatment outcome; leukemia; overall survival; myeloproliferative disorder; clinical trial; neutropenia; review; doxorubicin; fluorouracil; placebo; cancer combination chemotherapy; cancer risk; monotherapy; antineoplastic agents; paclitaxel; adjuvant therapy; chemotherapy, adjuvant; methotrexate; cancer staging; lymph node metastasis; cancer diagnosis; neoplasm staging; cancer grading; metastasis; multiple cycle treatment; breast cancer; gene expression profiling; mastectomy; stomatitis; drug administration schedule; epidermal growth factor receptor 2; aromatase inhibitor; genetic association; combination chemotherapy; cyclophosphamide; cell differentiation; drug effect; breast neoplasms; histology; docetaxel; asthenia; drug dose escalation; drug hypersensitivity; febrile neutropenia; adverse outcome; early cancer; adjuvant chemotherapy; cardiotoxicity; cancer size; comorbidity; tamoxifen; epirubicin; receptor, erbb-2; receptors, estrogen; hormonal therapy; taxane derivative; estrogen receptor; trastuzumab; anastrozole; navelbine; postmenopause; granulocyte colony stimulating factor; clinical trials; neoplasms, hormone-dependent; amenorrhea |
| Journal Title: | Hematology/Oncology Clinics of North America |
| Volume: | 21 |
| Issue: | 2 |
| ISSN: | 0889-8588 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2007-05-01 |
| Start Page: | 207 |
| End Page: | 222 |
| Language: | English |
| DOI: | 10.1016/j.hoc.2007.03.008 |
| PUBMED: | 17512445 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 1" - "Export Date: 17 November 2011" - "CODEN: HCNAE" - "Source: Scopus" |
Altmetric
Citation Impact
BMJ Impact Analytics
Related MSK Work