Communication and ethical considerations for fertility preservation for patients with childhood, adolescent, and young adult cancer: Recommendations from the PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group Guidelines
| Authors: | Mulder, R. L.; Font-Gonzalez, A.; van Dulmen-den Broeder, E.; Quinn, G. P.; Ginsberg, J. P.; Loeffen, E. A. H.; Hudson, M. M.; Burns, K. C.; van Santen, H. M.; Berger, C.; Diesch, T.; Dirksen, U.; Giwercman, A.; Gracia, C.; Hunter, S. E.; Kelvin, J. F.; Klosky, J. L.; Laven, J. S. E.; Lockart, B. A.; Neggers, S. J. C. M. M.; Peate, M.; Phillips, B.; Reed, D. R.; Tinner, E. M. E.; Byrne, J.; Veening, M.; van de Berg, M.; Verhaak, C. M.; Anazodo, A.; Rodriguez-Wallberg, K.; van den Heuvel-Eibrink, M. M.; Asogwa, O. A.; Brownsdon, A.; Wallace, W. H.; Green, D. M.; Skinner, R.; Haupt, R.; Kenney, L. B.; Levine, J.; van de Wetering, M. D.; Tissing, W. J. E.; Paul, N. W.; Kremer, L. C. M.; Inthorn, J.; on behalf of the PanCareLIFE Consortium |
| Title: | Communication and ethical considerations for fertility preservation for patients with childhood, adolescent, and young adult cancer: Recommendations from the PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group |
| Abstract: | Patients with childhood, adolescent, and young adult cancer who will be treated with gonadotoxic therapies are at increased risk for infertility. Many patients and their families desire biological children but effective communication about treatment-related infertility risk and procedures for fertility preservation does not always happen. The PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group reviewed the literature and developed a clinical practice guideline that provides recommendations for ongoing communication methods for fertility preservation for patients who were diagnosed with childhood, adolescent, and young adult cancer at age 25 years or younger and their families. Moreover, the guideline panel formulated considerations of the ethical implications that are associated with these procedures. Grading of Recommendations Assessment, Development and Evaluation methodology was used to grade the evidence and recommendations. In this clinical practice guideline, existing evidence and international expertise are combined to develop transparent recommendations that are easy to use to facilitate ongoing communication between health-care providers and patients with childhood, adolescent, and young adult cancer who might be at high risk for fertility impairment and their families. © 2021 Elsevier Ltd |
| Journal Title: | Lancet Oncology |
| Volume: | 22 |
| Issue: | 2 |
| ISSN: | 1470-2045 |
| Publisher: | Elsevier Science, Inc. |
| Date Published: | 2021-02-01 |
| Start Page: | e68 |
| End Page: | e80 |
| Language: | English |
| DOI: | 10.1016/s1470-2045(20)30595-7 |
| PUBMED: | 33539755 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review; Acknowledgements: Zoltan Antal - External reviewer -- Export Date: 1 March 2021 -- Source: Scopus |
