Anti-epidermal growth factor receptor monoclonal antibodies may inhibit A431 tumor cell proliferation by blocking an autocrine pathway Conference Paper
| Authors: | Mendelsohn, J.; Masui, H.; Goldenberg, A. |
| Title: | Anti-epidermal growth factor receptor monoclonal antibodies may inhibit A431 tumor cell proliferation by blocking an autocrine pathway |
| Conference Title: | 100th Session of the Association of American Physicians |
| Abstract: | Monoclonal antibodies which bind to the EGF receptor have the capacity to inhibit EGF-induced effects upon proliferation and biochemical functions in cultured human cells. Some EGF receptor-bearing tumor cells are prevented from growth by treatment with antireceptor antibody. Evidence is presented which suggests that antibody-mediated antiproliferative activity may result from effects upon growth factor-dependent processes in the receptor-bearing cells. |
| Keywords: | epidermal growth factor; squamous cell carcinoma; carcinoma, squamous cell; cell division; epidermal growth factor receptor; cell line; receptor, epidermal growth factor; physiology; monoclonal antibody; immunology; antibodies, monoclonal; humans; human; article |
| Journal Title | Transactions of the Association of American Physicians |
| Volume: | C |
| Conference Dates: | 1987 May 1-4 |
| Conference Location: | San Diego, CA |
| ISBN: | 0066-9458 |
| Publisher: | Wiley-Blackwell Publishing, Inc. |
| Date Published: | 1987-01-01 |
| Start Page: | 173 |
| End Page: | 178 |
| Language: | English |
| PUBMED: | 3502661 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 5 February 2021 -- Source: Scopus |
