A human monoclonal antibody against HLA‐A25 Journal Article
| Authors: | Kosinski, S.; Ferrara, G. B.; Yang, S. Y.; Hämmerling, U. |
| Article Title: | A human monoclonal antibody against HLA‐A25 |
| Abstract: | We are reporting the production and characterization of a human monoclonal antibody recognizing antigen HLA‐25. The antibody was developed by a line transformed in vitro by the Epstein‐Barr virus. The immune B lymphocytes for transformation were generated by planned immunization of a volunteer with repeated doses of allogenic peripheral blood lymphocytes of one donor over the course of 7 years. The antibody showed correlation with A25 antigen on a panel of 244 individuals tested by microcytotoxicity. The antibody showed neither cytotoxic reactivity nor CYNAP phenomenon with antigens of HLA‐10 CREG. Copyright © 1987, Wiley Blackwell. All rights reserved |
| Keywords: | b-lymphocytes; monoclonal antibody; lymphocyte activation; antibodies, monoclonal; cytotoxicity, immunologic; clone cells; hla antigens; herpesvirus 4, human; in vitro; epitopes; human; priority journal; beta 2-microglobulin; support, non-u.s. gov't; support, u.s. gov't, p.h.s. |
| Journal Title: | Tissue Antigens |
| Volume: | 29 |
| Issue: | 4 |
| ISSN: | 0001-2815 |
| Publisher: | Wiley-Blackwell Publishing, Inc. |
| Date Published: | 1987-04-01 |
| Start Page: | 177 |
| End Page: | 183 |
| Language: | English |
| DOI: | 10.1111/j.1399-0039.1987.tb01573.x |
| PUBMED: | 2441487 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 5 February 2021 -- Source: Scopus |
