Intraperitoneal cisplatin chemotherapy Journal Article

  


Author: Markman, M.
Article Title: Intraperitoneal cisplatin chemotherapy
Abstract: The intraperitoneal delivery of cisplatin as treatment of tumors principally confined to the peritoneal cavity (such as ovarian carcinoma and mesothelioma) is based on sound pharmacological principles. Early phase clinical trials have confirmed both the pharmacokinetic advantage and the safety of this approach. Objective responses (including surgically defined complete remissions) have been observed in patients with refractory ovarian carcinoma who have failed systemically delivered cisplatin, confirming the potential superiority of this technique over standard methods of cisplatin administration.
Keywords: cancer chemotherapy; review; cisplatin; ovary carcinoma; mesothelioma; short survey; pharmacokinetics; intraperitoneal drug administration; human
Journal Title: ISI Atlas of Science: Pharmacology
Volume: 1
Issue: 3
ISSN: 0890-9083
Publisher: Thomson Reuters  
Date Published: 1987-01-01
Start Page: 225
End Page: 227
Language: English
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023515425&partnerID=40&md5=7c2e8f90ba4b6b5c55e6d1050af14427
Notes: Article -- Export Date: 5 February 2021 -- Source: Scopus