Allelic variants of Ly-5 in inbred and natural populations of mice Journal Article
| Authors: | Seldin, M. F.; D'Hoostelaere, L. A.; Steinberg, A. D.; Saga, Y.; Morse, H. C. 3rd |
| Article Title: | Allelic variants of Ly-5 in inbred and natural populations of mice |
| Abstract: | Allelic variants of Ly-5 in inbred commensal and other natural populations of mice were analyzed by patterns of restriction fragment length polymorphisms (RFLP) and Southern hybridization using an Ly-5 cDNA probe and by cell-surface staining with a panel of antibodies directed against polymorphic and nonpolymorphic Ly-5 determinants. New Ly-5 alleles were defined by RFLPs generated by both Eco RI and Bam HI restriction enzyme digests. The Mus musculus subspecies and other species within the genus Mus showed a strong correlation between allelic variants defined by restriction enzymes and serologic specificities. The data also suggest the conservation of the Ly-5 gene throughout the genus Mus. © 1987 Springer-Verlag. |
| Keywords: | nonhuman; animal cell; mouse; cytology; animals; mice; heredity; alleles; mice, inbred strains; species specificity; genetic engineering; radioisotope; antigens, ly; cell surface; restriction fragment length polymorphism; polymorphism, restriction fragment length; population genetics; priority journal |
| Journal Title: | Immunogenetics |
| Volume: | 26 |
| Issue: | 1-2 |
| ISSN: | 0093-7711 |
| Publisher: | Springer |
| Date Published: | 1987-01-01 |
| Start Page: | 74 |
| End Page: | 78 |
| Language: | English |
| DOI: | 10.1007/bf00345457 |
| PUBMED: | 2886425 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 5 February 2021 -- Source: Scopus |
