Nucleosides. CXLIII. Synthesis of 5’-deoxy-5’-substituted-2,2’-anhydro-l-(β-D-arabinofuranosyl)uracils. A new 2,5’- to 2,2’-anhydro-nucleoside transformation. Studies directed toward the synthesis of 2‘-deoxy-2’-substituted arabino nucleosides. (4) Journal Article

  

Authors:	Pankiewicz, K. W.; Watanabe, K. A.
Article Title:	Nucleosides. CXLIII. Synthesis of 5’-deoxy-5’-substituted-2,2’-anhydro-l-(β-D-arabinofuranosyl)uracils. A new 2,5’- to 2,2’-anhydro-nucleoside transformation. Studies directed toward the synthesis of 2‘-deoxy-2’-substituted arabino nucleosides. (4)
Abstract:	Treatment of 2,5’-anhydro-3’-O-acetyl-2’-O-triflyluridine with a nucleophile such as NaOAc, NaN3, LiCl or LiBr, did not afford the 2’-substituted 2,5’-anhydro-arabinosyluracil, but gave 2,2’-anhydro-l-(5-substituted-β-D-arabinofuranosyl)uracil instead. © 1987, The Pharmaceutical Society of Japan. All rights reserved.
Keywords:	unclassified drug; nonhuman; methodology; chemistry; arabinofuranosyluracil; uridine; acetylation; arabinonucleosides; support, u.s. gov't, p.h.s.; drug analysis; 2‘-anhydroabinosyluracil new transformation; 2’-anhydrouracilnucleoside 2; 5‘-anhydro-3‘-o-acetyl-2‘; 5’-anhydrouracilnucleoside 2; nucleoside anhydronucleoside 2; o-triflyluridine 5‘-substituted-2; 2,2' anhydrouracil arabinoside derivative
Journal Title:	Chemical and Pharmaceutical Bulletin
Volume:	35
Issue:	11
ISSN:	0009-2363
Publisher:	Pharmaceutical Society of Japan
Date Published:	1987-11-25
Start Page:	4494
End Page:	4497
Language:	English
DOI:	10.1248/cpb.35.4494
PUBMED:	3442883
PROVIDER:	scopus
DOI/URL:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-0042922008&doi=10.1248%2fcpb.35.4494&partnerID=40&md5=1b2cc701d176429b757ee620f72080eb
Notes:	Article -- Export Date: 5 February 2021 -- Source: Scopus

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