Primitive neuroectodermal tumor cell lines: Chromosomal analysis of five cases Journal Article
| Authors: | Potluri, V. R.; Gilbert, F.; Helsen, C.; Helson, L. |
| Article Title: | Primitive neuroectodermal tumor cell lines: Chromosomal analysis of five cases |
| Abstract: | A cytogenetic analysis of primitive neuroectodermal tumor (PNET) cell lines was undertaken. PNET are presumed to be embryologically related to, but clinically and histologically distinct from, other tumors of neuroectodermal origin, including neuroblastoma and retinoblastoma. No single chromosome abnormality was found in all five of the tumors studied. In three of the five cases, however, additional 1q material [either as extra chromosome #1 or i(1q)] was found in all cells, and in two of the five, monosomy 13 was noted in all cells; the possible significance of these findings is discussed. © 1987. |
| Keywords: | case report; heredity; cell line; histology; chromosome aberration; tumor cell; neoplasms, germ cell and embryonal; chromosome aberrations; karyotyping; neuroectoderm tumor; nervous system; etiology; neuroectoderm; human; priority journal; support, u.s. gov't, p.h.s.; chromosome 1 aberration; monosomy 13 |
| Journal Title: | Cancer Genetics and Cytogenetics |
| Volume: | 24 |
| Issue: | 1 |
| ISSN: | 0165-4608 |
| Publisher: | Elsevier Science, Inc. |
| Date Published: | 1987-01-01 |
| Start Page: | 75 |
| End Page: | 86 |
| Language: | English |
| DOI: | 10.1016/0165-4608(87)90084-7 |
| PUBMED: | 3024811 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 5 February 2021 -- Source: Scopus |
