Malignant lymphoma of the breast: A study of 53 patients Journal Article


Authors: Brustein, S.; Kimmel, M.; Lieberman, P. H.; Filippa, D. A.; Rosen, P. P.
Article Title: Malignant lymphoma of the breast: A study of 53 patients
Abstract: Fifty-three patients with non-Hodgkin's lymphoma of the breast were reviewed and classified using four current classifications of lymphoma. All patients were female with a mean age of 57 years. The majority of patients had histiocytic or large-cell lesions and presented as clinical Stage I. The tumors were described clinically as primary in the breast, and mammary parenchyma was found in 79% of the diagnostic biopsy specimens. The other specimens showed lymphoma in mammary adipose tissue. Survival was not influenced by the presence or absence of breast parenchyma in the biopsy. Statistically significant survival differences were found to be related to stage at presentation as well as to tumor grade, using Kiel and Working Formulation categories. Patients with Stage I disease and those with low-grade lesions had a more favorable prognosis. No discernible factors, including stage or histologic findings, appeared to affect the recurrence rate.
Keywords: clinical article; cancer staging; breast cancer; breast; biopsy; histology; lymphatic system; nonhodgkin lymphoma; diagnosis; lymphoma; therapy; prognosis; human; priority journal
Journal Title: Annals of Surgery
Volume: 205
Issue: 2
ISSN: 0003-4932
Publisher: Lippincott Williams & Wilkins  
Date Published: 1987-02-01
Start Page: 144
End Page: 150
Language: English
DOI: 10.1097/00000658-198702000-00008
PUBMED: 3545107
PROVIDER: scopus
PMCID: PMC1492821
DOI/URL:
Notes: Article -- Export Date: 5 February 2021 -- Source: Scopus
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  1. Daniel A Filippa
    148 Filippa
  2. Paul P Rosen
    201 Rosen
  3. Marek Kimmel
    46 Kimmel