Short-term outcomes following virtual surgery-assisted immediate dental implant placement in free fibula flaps for oncologic mandibular reconstruction Journal Article


Authors: Allen, R. J. Jr; Nelson, J. A.; Polanco, T. O.; Shamsunder, M. G.; Ganly, I.; Boyle, J.; Rosen, E.; Matros, E.
Article Title: Short-term outcomes following virtual surgery-assisted immediate dental implant placement in free fibula flaps for oncologic mandibular reconstruction
Abstract: Background: Despite reports demonstrating feasibility of immediate dental implant placement in mandibular reconstruction with free fibula flaps for benign disease, this practice is not routinely used in the oncologic setting. The authors aim to demonstrate the safety of immediate dental implant placement for oncologic mandible reconstruction. Methods: In 2017, the authors' center began immediate dental implant placement in free fibula flaps for oncologic patients undergoing mandibulectomy reconstruction. Immediate dental implant placement patients were compared to a historical cohort also reconstructed with computer-aided design and manufacturing technology beginning in 2011 (n = 34) as a noninferiority study design. Primary outcomes of interest included 90-day complications, time to radiotherapy, and time to and number of patients achieving dental restoration. Results: Sixty-one patients underwent free fibula flaps following mandibulectomy using computer-aided design and manufacturing. Seventy-two dental implants were placed in the immediate dental implant placement cohort (n = 27). No differences were noted in major or minor 90-day complications between groups (p > 0.05). Radiotherapy was required in 55 percent in the immediate dental implant placement cohort versus 62 percent in the historical cohort, with no significant difference in time to radiotherapy (67.6 days versus 62.2 days, respectively). One dental implant was removed for nonosseointegration noted during vestibuloplasty. Fourteen (51.8 percent) immediate dental implant patients had complete dental restoration at 90 days compared with none in the historical cohort (p < 0.05). Conclusions: Immediate dental implant placement is a safe procedure with an unchanged short-term complication profile and no delay in radiotherapy initiation. Patients undergoing immediate dental implant placement are more likely to complete full dental rehabilitation. Long-term and health-related quality-of-life outcomes remain to be determined.
Keywords: rehabilitation; optimization; head; jaw; surface; osteoseptocutaneous free-flap
Journal Title: Plastic and Reconstructive Surgery
Volume: 146
Issue: 6
ISSN: 0032-1052
Publisher: Lippincott Williams & Wilkins  
Date Published: 2020-12-01
Start Page: 768e
End Page: 776e
Language: English
ACCESSION: WOS:000592044600008
DOI: 10.1097/prs.0000000000007352
PROVIDER: wos
PMCID: PMC7737649
PUBMED: 33234971
Notes: Article -- Source: Wos
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MSK Authors
  1. Jay O Boyle
    148 Boyle
  2. Evan Matros
    201 Matros
  3. Ian Ganly
    429 Ganly
  4. Evan Blake Rosen
    28 Rosen
  5. Jonas Allan Nelson
    208 Nelson
  6. Thais O Polanco
    24 Polanco