Immediate dental implants in fibula free flaps to reconstruct the mandible: A pilot study of the short-term effects on radiotherapy for patients with head and neck cancer Journal Article
| Authors: | Sandoval, M. L.; Rosen, E. B.; Robert, A. J.; Nelson, J. A.; Matros, E.; Gelblum, D. Y. |
| Article Title: | Immediate dental implants in fibula free flaps to reconstruct the mandible: A pilot study of the short-term effects on radiotherapy for patients with head and neck cancer |
| Abstract: | Objectives: The current pilot study aims to report short-term experience as it relates to acute radiotherapy treatment outcomes comparing patients with immediate dental implants in fibula free flap reconstructions to a historical cohort of patients with fibula free flap reconstructions without dental implants. Materials and methods: A retrospective review of patients who underwent segmental mandibulectomy, reconstruction with fibula free flaps, and adjuvant radiotherapy with (n = 10) and without immediate dental implants (n = 10) at a tertiary cancer center from 2015 to 2018 was performed (IRB #17-271). Incidence of postoperative complications, time to initiation of radiation therapy, development of acute toxicity, and patient reported outcome data were recorded. The radiation plans were evaluated to identify the mean and maximum doses received by the mandible and oral cavity as well as the locations of radiation global hot spots. Results: There was a similar number of postoperative complications in both cohorts, with three events in the case group and two events in the control group. Patients with dental implants reported less trismus than control patients. Evaluation of the radiation treatment plans revealed similar median radiation global hot spots in both groups. Conclusions: The current study suggests that the presence of dental implants does not increase the risk of complications following surgery or during radiation treatment. Implants do not alter radiation dosimetry but do appear to positively impact early patient quality of life. Although longer follow-up is needed, based on this preliminary experience, cancer patients should be offered this type of reconstruction without fear of impacting radiation timing or delivery. © 2019 Wiley Periodicals, Inc. |
| Keywords: | treatment outcome; bone transplantation; reconstructive surgical procedures; retrospective studies; surgical flaps; quality of life; radiotherapy; retrospective study; pilot study; head and neck neoplasms; pilot projects; free tissue graft; head and neck tumor; mandible; mandibular neoplasms; oral cancer; mandible tumor; free tissue flaps; dental implants; reconstructive surgery; humans; human; tooth implant |
| Journal Title: | Clinical Implant Dentistry and Related Research |
| Volume: | 22 |
| Issue: | 1 |
| ISSN: | 1523-0899 |
| Publisher: | Wiley Periodicals, Inc |
| Date Published: | 2020-02-01 |
| Start Page: | 91 |
| End Page: | 95 |
| Language: | English |
| DOI: | 10.1111/cid.12870 |
| PUBMED: | 31777154 |
| PROVIDER: | scopus |
| PMCID: | PMC9348905 |
| DOI/URL: | |
| Notes: | Robert J. Allen's first and last names are reversed on the original publication -- Article -- Export Date: 1 April 2020 -- Source: Scopus |
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