Intraarterial chemotherapy for liver metastases Review


Authors: Connell, L. C.; Kemeny, N. E.
Review Title: Intraarterial chemotherapy for liver metastases
Abstract: Colorectal cancer (CRC) is one of the leading cancers globally in terms of both incidence and cancer-related mortality. Liver metastatic disease is the main prognostic driver for patients with CRC. The management options for liver metastatic CRC continue to evolve, particularly with the incorporation of locoregional therapies into the treatment paradigm. Hepatic arterial infusion (HAI) chemotherapy is one such liver directed approach used with the goal of converting patients to liver resection, reducing the risk of recurrence, treating recurrent disease, and most importantly improving overall survival. This article summarizes the role of HAI chemotherapy in the treatment of liver metastatic CRC. © 2020 Elsevier Inc.
Keywords: survival; colorectal cancer; intrahepatic cholangiocarcinoma; hepatic arterial infusion chemotherapy; conversion to resection
Journal Title: Surgical Oncology Clinics of North America
Volume: 30
Issue: 1
ISSN: 1055-3207
Publisher: Elsevier Inc.  
Date Published: 2021-01-01
Start Page: 143
End Page: 158
Language: English
DOI: 10.1016/j.soc.2020.08.005
PUBMED: 33220802
PROVIDER: scopus
PMCID: PMC8594481
DOI/URL:
Notes: Review; Chapter in D'Angelica M, ed. "Management of Metastatic Liver Tumors" (ISBN: 978-0-323-76449-0) -- Export Date: 4 January 2021 -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Nancy Kemeny
    543 Kemeny
  2. Louise Catherine Connell
    45 Connell