Authors: | Dalvi, N.; Kleinerman, R. A.; Epelman, S.; Abramson, D. H.; Dunkel, I. J. |
Article Title: | Low-grade glioma: A rare second tumor in retinoblastoma survivors |
Abstract: | Retinoblastoma survivors with a germline RB1 mutation are at elevated risk for secondary (nonocular) malignancy, but their risk for low-grade glioma (LGG) is unknown. We performed a retrospective review of the Memorial Sloan Kettering Cancer Center and the NCI databases that revealed that three of the 837 5-year survivors of hereditary retinoblastoma were diagnosed with an LGG and a fourth patient (but unilateral and without a germline mutation) was identified at another center. Retinoblastoma survivors may be at increased risk for LGG. © 2020 Wiley Periodicals LLC |
Keywords: | retinoblastoma; survivorship; low-grade glioma; second cancers |
Journal Title: | Pediatric Blood and Cancer |
Volume: | 68 |
Issue: | 2 |
ISSN: | 1545-5009 |
Publisher: | Wiley Periodicals, Inc |
Date Published: | 2021-02-01 |
Start Page: | e28770 |
Language: | English |
DOI: | 10.1002/pbc.28770 |
PUBMED: | 33063942 |
PROVIDER: | scopus |
PMCID: | PMC8376183 |
DOI/URL: | |
Notes: | Article -- Export Date: 4 January 2021 -- Source: Scopus |