Oncoplastic breast-conserving therapy and intraoperative radiotherapy for management of carcinoma in situ of the breast: A single-center experience Research Letter


Authors: Crown, A.; Carlson, E.; Rocha, F. G.; Grumley, J. W.
Title: Oncoplastic breast-conserving therapy and intraoperative radiotherapy for management of carcinoma in situ of the breast: A single-center experience
Abstract: Intraoperative radiation therapy (IORT) has been shown to reduce local recurrence rates among women with early-stage invasive ductal carcinoma, but data regarding its use among women with in situ carcinoma are limited. In this single-institution study, 50 women with in situ carcinoma were treated with oncoplastic breast-conserving surgery (OPS) and single-dose IORT. All 50 patients had “no tumor on ink,” but 9 (16%) had margins < 2 mm and required additional therapy. No local recurrences were observed after a median follow-up of 46 months. Single-dose IORT is an efficacious treatment for well-selected patients with DCIS. © 2020 Wiley Periodicals LLC
Keywords: ductal carcinoma in situ; early stage breast cancer; intraoperative radiation therapy
Journal Title: Breast Journal
Volume: 26
Issue: 12
ISSN: 1075-122X
Publisher: Wiley Blackwell  
Date Published: 2020-12-01
Start Page: 2391
End Page: 2394
Language: English
DOI: 10.1111/tbj.14093
PUBMED: 33283376
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 4 January 2021 -- Source: Scopus
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  1. Angelena Crown
    28 Crown