Outcome following removal of infected tissue expanders in breast reconstruction: A 10-year experience Journal Article


Authors: Halvorson, E. G.; Disa, J. J.; Mehrara, B. J.; Burkey, B. A.; Pusic, A. L.; Cordeiro, P. G.
Article Title: Outcome following removal of infected tissue expanders in breast reconstruction: A 10-year experience
Abstract: Although several studies have analyzed risk factors for tissue expander removal prior to permanent implant placement in breast reconstruction, the outcome following explantation because of infection is unknown. From a prospectively maintained database covering a 10-year period, 39 such patients were identified. Twelve (30.8%) had prior radiotherapy. Nine patients (23%) underwent reexpansion, 3 (7.7%) had a latissimus dorsi flap and expander, and 1 (2.6%) received a free transverse rectus abdominis flap. Recurrent infection occurred in 1 reexpanded patient. Two patients developed late contractures. All other reconstructions were successful. Twenty-six patients (66.7%) did not undergo secondary reconstruction, most commonly due to a combination of patient preference, cancer progression, and radiotherapy. After removal of an infected expander, most patients who are interested and remain good candidates can still be reconstructed. Reexpansion was successful in patients without prior radiotherapy. Secondary reconstruction with autologous tissue is appropriate when there is a history of radiotherapy. © 2007 Lippincott Williams & Wilkins, Inc.
Keywords: adult; controlled study; treatment outcome; middle aged; implant; major clinical study; cancer growth; cancer radiotherapy; prospective studies; infection; radiation; radiotherapy; breast reconstruction; mammaplasty; latissimus dorsi flap; device removal; prosthesis-related infections; tissue expansion; time factors; recurrent disease; outcome; infection risk; tissue expander; expansion; secondary; delayed; removal; explantation; tissue expanders
Journal Title: Annals of Plastic Surgery
Volume: 59
Issue: 2
ISSN: 0148-7043
Publisher: Lippincott Williams & Wilkins  
Date Published: 2007-08-01
Start Page: 131
End Page: 136
Language: English
DOI: 10.1097/01.sap.0000252716.73356.68
PUBMED: 17667404
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 3" - "Export Date: 17 November 2011" - "CODEN: APCSD" - "Source: Scopus"
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MSK Authors
  1. Joseph Disa
    262 Disa
  2. Andrea Pusic
    300 Pusic
  3. Babak Mehrara
    448 Mehrara
  4. Peter G Cordeiro
    282 Cordeiro
  5. Brooke A Burkey
    1 Burkey