Immediate tissue expander/implast breast reconstruction after salvage mastectomy for cancer recurrence following lumpectomy/irradiation Journal Article
| Authors: | Cordeiro, P. G.; Snell, L.; Heerdt, A.; Mccarthy, C. |
| Article Title: | Immediate tissue expander/implast breast reconstruction after salvage mastectomy for cancer recurrence following lumpectomy/irradiation |
| Abstract: | Background: The objective of this study was to analyze early complications and long-term outcomes in patients undergoing salvage mastectomy and immediate tissue expander/implant reconstruction for cancer recurrence following breast conservation therapy (lumpectomy/irradiation). Methods: A review of all tissue expander/implant reconstructions performed by a single surgeon over an 11-year period from 1997 to 2008 was performed. Two patient cohorts were identified: (1) patients who underwent salvage mastectomy for a cancer recurrence following prior breast conservation therapy, and (2) patients who underwent primary mastectomy without a history of prior irradiation. The incidence of early complications and long-term outcomes were determined for each cohort. Results: Immediate, tissue expander/implant reconstruction was initiated in 1699 patients. One hundred twenty-one patients had a history of breast conservation therapy (lumpectomy/irradiation), and 1578 did not have a history of prior irradiation. The incidence of early complications was significantly higher in the irradiated cohort compared with that in the nonirradiated cohort (29.7 percent versus 15.5 percent; p ≤ 0.001). The most common complication in both groups was mastectomy flap necrosis (18.0 percent in the irradiated group and 7.7 percent in the nonirradiated group; p < 0.001). Six hundred ninety-seven patients had long-term follow-up data available. Most previously irradiated patients had good or very good results, whereas most nonirradiated patients had excellent results (p = 0.04; Mann-Whitney U test). Conclusions: Carefully selected patients who have had prior breast conservation therapy who require salvage mastectomy can successfully complete postmastectomy tissue expander/implant reconstruction. The rate of early complications in this patient group is higher than in the nonirradiated cohort but remains acceptable. Copyright © 2012 by the American Society of Plastic Surgeons. |
| Journal Title: | Plastic and Reconstructive Surgery |
| Volume: | 129 |
| Issue: | 2 |
| ISSN: | 0032-1052 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2012-02-01 |
| Start Page: | 341 |
| End Page: | 350 |
| Language: | English |
| DOI: | 10.1097/PRS.0b013e318205f203 |
| PROVIDER: | scopus |
| PUBMED: | 22286416 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 1 March 2012" - "CODEN: PRSUA" - "Source: Scopus" |
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