Laterality and patient-reported outcomes following autologous breast reconstruction with free abdominal tissue: An 8-year examination of BREAST-Q data Journal Article


Authors: Allen, R. J. Jr; Sobti, N.; Patel, A. R.; Matros, E.; McCarthy, C. M.; Dayan, J. H.; Disa, J. J.; Mehrara, B. J.; Morrow, M.; Pusic, A. L.; Nelson, J. A.
Article Title: Laterality and patient-reported outcomes following autologous breast reconstruction with free abdominal tissue: An 8-year examination of BREAST-Q data
Abstract: Background: Despite the rise in rates of contralateral prophylactic mastectomy, few studies have used patient-reported outcomes to assess satisfaction between unilateral and bilateral breast reconstruction with autologous tissue. The purpose of this study was to investigate patient satisfaction and quality of life following autologous reconstruction to determine whether differences exist between unilateral and bilateral reconstructions to better guide clinical decision-making. Methods: The current study examined prospectively collected BREAST-Q results following abdominal free flap breast reconstruction procedures performed at a tertiary academic medical center from 2009 to 2017. The reconstruction module of the BREAST-Q was used to assess outcomes between laterality groups (unilateral versus bilateral) at 1 year, 2 years, 3 years, and more than 3 years. Results: Overall, 405 patients who underwent autologous breast reconstruction completed the BREAST-Q. Cross-sectional analysis at 1 year, 2 years, and 3 years revealed similar satisfaction scores between groups; however, bilateral reconstruction patients demonstrated higher satisfaction scores at more than 3 years (p = 0.04). Bilateral reconstruction patients reported lower scores of abdominal well-being at 1 year, 2 years, and more than 3 years (p = 0.01, p = 0.03, and p = 0.01, respectively). Conclusions: These results suggest that satisfaction with breasts does not differ with the laterality of the autologous reconstruction up to 3 years postoperatively but may diverge thereafter. Bilateral reconstruction patients, however, have lower satisfaction with the abdominal donor site. These data can be used in preoperative counseling, informed consent, and expectations management in patients considering contralateral prophylactic mastectomy.
Keywords: complications; cost; impact; women; trends; functional; risk-factors; implants; contralateral prophylactic mastectomy; cancer patients; free tram flaps
Journal Title: Plastic and Reconstructive Surgery
Volume: 146
Issue: 5
ISSN: 0032-1052
Publisher: Lippincott Williams & Wilkins  
Date Published: 2020-11-01
Start Page: 964
End Page: 975
Language: English
ACCESSION: WOS:000583089000047
DOI: 10.1097/prs.0000000000007239
PROVIDER: wos
PUBMED: 33141527
PMCID: PMC8435215
Notes: Article -- Source: Wos
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MSK Authors
  1. Monica Morrow
    777 Morrow
  2. Joseph Disa
    265 Disa
  3. Andrea Pusic
    300 Pusic
  4. Babak Mehrara
    462 Mehrara
  5. Evan Matros
    210 Matros
  6. Colleen Marie McCarthy
    144 McCarthy
  7. Joseph Henry Dayan
    101 Dayan
  8. Robert J Allen Jr
    102 Allen Jr
  9. Jonas Allan Nelson
    225 Nelson
  10. Nikhil Sobti
    6 Sobti
  11. Aadit R Patel
    7 Patel