Long-term patient-reported satisfaction after contralateral prophylactic mastectomy and implant reconstruction Journal Article
| Authors: | Koslow, S.; Pharmer, L. A.; Scott, A. M.; Stempel, M.; Morrow, M.; Pusic, A. L.; King, T. A. |
| Article Title: | Long-term patient-reported satisfaction after contralateral prophylactic mastectomy and implant reconstruction |
| Abstract: | Purpose: To determine whether satisfaction and health-related quality of life (HR-QoL) differ between women who do and do not undergo contralateral prophylactic mastectomy (CPM) in the setting of implant reconstruction using the BREAST-Q, a validated patient-reported outcome instrument. Methods: From 2000 to 2007, a total of 3,874 patients with stage 0 to III unilateral breast cancer (BC) had mastectomy; 688 (18 %) pursued CPM within 1 year. Patients who completed the BREAST-Q reconstruction module as part of BREAST-Q validation studies or routine clinical care formed our study cohort. Comparisons were made between CPM and no-CPM patients using univariate analysis and multivariate models (MVA). Results: Of 294 patients with BREAST-Q data, 112 (38 %) had CPM. Median time from mastectomy to BREAST-Q was 52 months. CPM patients were younger (mean 47 vs. 50 years), more likely to be White (98 vs. 86 %), married (84 vs. 71 %), have a family history of BC (60 vs. 44 %), and to choose silicone implants (67 vs. 48 %). There were no differences in tumor or treatment characteristics between groups at the time of BREAST-Q. Patients with CPM had a higher mean score for Satisfaction with Breasts (64.4 vs. 54.9; p < 0.001) and Satisfaction with Outcome (74.8 vs. 67.7; p = 0.007); other HR-QoL domains did not differ. On MVA, CPM and the absence of lymphedema were significant predictors of Satisfaction with Breasts (CPM p = 0.005, lymphedema p = 0.039). CPM was not associated with improved Satisfaction with Outcome. Conclusions: This study suggests that in the setting of implant reconstruction, CPM has a positive correlation with patient satisfaction with their breasts, but not with improvements in other HR-QoL domains. © 2013 Society of Surgical Oncology. |
| Journal Title: | Annals of Surgical Oncology |
| Volume: | 20 |
| Issue: | 11 |
| ISSN: | 1068-9265 |
| Publisher: | Springer |
| Date Published: | 2013-10-01 |
| Start Page: | 3422 |
| End Page: | 3429 |
| Language: | English |
| DOI: | 10.1245/s10434-013-3026-2 |
| PROVIDER: | scopus |
| PUBMED: | 23720070 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 1 October 2013" - "CODEN: ASONF" - "Source: Scopus" |
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