External beam radiation therapy for liver metastases Review


Authors: Romesser, P. B.; Neal, B. P.; Crane, C. H.
Review Title: External beam radiation therapy for liver metastases
Abstract: Stereotactic ablative radiotherapy (SABR) commonly is used for small liver metastases. Modern conformal radiotherapy techniques, including 3-dimensional conformal radiotherapy and intensity-modulated radiation therapy, enable the safe delivery of SABR to small liver volumes. For larger tumors, the safe delivery of SABR can be challenging due to a more limited volume of healthy normal liver parenchyma and the proximity of the tumor to radiosensitive organs, such as the stomach, duodenum, and large intestine. Controlling respiratory motion, the use of image guidance, and increasing the number of radiation fractions sometimes are necessary for the safe delivery of SABR in these situations. © 2020 Elsevier Inc.
Keywords: liver metastasis; radiation therapy; tumor control probability; proton therapy; external beam radiation; stereotactic body; ablative radiation; moderate hypofractionation
Journal Title: Surgical Oncology Clinics of North America
Volume: 30
Issue: 1
ISSN: 1055-3207
Publisher: Elsevier Inc.  
Date Published: 2021-01-01
Start Page: 159
End Page: 173
Language: English
DOI: 10.1016/j.soc.2020.08.006
PUBMED: 33220803
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 1 December 2020 -- Source: Scopus
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  1. Paul Bernard Romesser
    189 Romesser
  2. Christopher   Crane
    201 Crane