Leveraging synthetic chlorins for bio-imaging applications Research Letter


Authors: Hernández-Gil, J.; Lewis, J. S.; Reiner, T.; Drain, C. M.; Gonzales, J.
Title: Leveraging synthetic chlorins for bio-imaging applications
Abstract: Synthetic chlorins are not only fluorescent, the modulation of the tetrapyrrole system can also chelate metal ions. Conjugation of linkers at their pyrrolidines allows for conjugation to bio-molecules to create target specificity. By altering these chemo-photophysical properties, this work facilitates the use of chlorins in fluorescent imaging and positron emission tomography (PET). © 2020 The Royal Society of Chemistry.
Keywords: positron emission tomography; fluorescent imaging; fluorescence imaging; metals; positron emission tomography (pet); pyrrolidines; metal ions; photophysical properties; article; bio-imaging; chlorins; tetrapyrroles
Journal Title: Chemical Communications
Volume: 56
Issue: 83
ISSN: 1359-7345
Publisher: Royal Society of Chemistry  
Date Published: 2020-10-25
Start Page: 12608
End Page: 12611
Language: English
DOI: 10.1039/d0cc05494a
PUBMED: 32945820
PROVIDER: scopus
PMCID: PMC7907923
DOI/URL:
Notes: Article -- Export Date: 1 December 2020 -- Source: Scopus
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  1. Jason S Lewis
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  2. Thomas Reiner
    136 Reiner