Leveraging synthetic chlorins for bio-imaging applications Research Letter

   


Authors: Hernández-Gil, J.; Lewis, J. S.; Reiner, T.; Drain, C. M.; Gonzales, J.
Title: Leveraging synthetic chlorins for bio-imaging applications
Abstract: Synthetic chlorins are not only fluorescent, the modulation of the tetrapyrrole system can also chelate metal ions. Conjugation of linkers at their pyrrolidines allows for conjugation to bio-molecules to create target specificity. By altering these chemo-photophysical properties, this work facilitates the use of chlorins in fluorescent imaging and positron emission tomography (PET). © 2020 The Royal Society of Chemistry.
Keywords: positron emission tomography; fluorescent imaging; fluorescence imaging; metals; positron emission tomography (pet); pyrrolidines; metal ions; photophysical properties; article; bio-imaging; chlorins; tetrapyrroles
Journal Title: Chemical Communications
Volume: 56
Issue: 83
ISSN: 1359-7345
Publisher: Royal Society of Chemistry  
Date Published: 2020-10-25
Start Page: 12608
End Page: 12611
Language: English
DOI: 10.1039/d0cc05494a
PUBMED: 32945820
PROVIDER: scopus
PMCID: PMC7907923
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85094220433&doi=10.1039%2fd0cc05494a&partnerID=40&md5=ff9e48818af564cbae49efee3102508b
Notes: Article -- Export Date: 1 December 2020 -- Source: Scopus
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MSK Authors
  1. Jason S Lewis
    461 Lewis
  2. Thomas Reiner
    136 Reiner
  3. Junior Gonzales
    9 Gonzales
  4. Javier Hernandez Hernandez Gil
    4 Hernandez Gil
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