A tug-of-war over methionine Editorial
| Authors: | Xu, K.; Shyu, A.; Li, M. O. |
| Title: | A tug-of-war over methionine |
| Abstract: | Nutrient acquisition and metabolism are integral components of cell growth, proliferation, and differentiation programs. In a recent study in Nature, Bian et al. (2020) revealed that cancer cells outcompete T cells for methionine uptake, resulting in diminished SAM production, attenuated H3K79 dimethylation, decreased STAT5 expression, and impaired T cell immunity to cancer. © 2020 Nutrient acquisition and metabolism are integral components of cell growth, proliferation, and differentiation programs. In a recent study in Nature, Bian et al. (2020) revealed that cancer cells outcompete T cells for methionine uptake, resulting in diminished SAM production, attenuated H3K79 dimethylation, decreased STAT5 expression, and impaired T cell immunity to cancer. © 2020 |
| Journal Title: | Cell Metabolism |
| Volume: | 32 |
| Issue: | 5 |
| ISSN: | 1550-4131 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2020-11-03 |
| Start Page: | 699 |
| End Page: | 701 |
| Language: | English |
| DOI: | 10.1016/j.cmet.2020.10.016 |
| PUBMED: | 33147482 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 1 December 2020 -- Source: Scopus |
Altmetric
Citation Impact
BMJ Impact Analytics
Related MSK Work