Gastrointestinal tissue-based molecular biomarkers: A practical categorisation based on the 2019 World Health Organization classification of epithelial digestive tumours Review
| Authors: | Quezada-Marín, J. I.; Lam, A. K.; Ochiai, A.; Odze, R. D.; Washington, K. M.; Fukayama, M.; Rugge, M.; Klimstra, D. S.; Nagtegaal, I. D.; Tan, P. H.; Arends, M. J.; Goldblum, J. R.; Cree, I. A.; Salto-Tellez, M. |
| Review Title: | Gastrointestinal tissue-based molecular biomarkers: A practical categorisation based on the 2019 World Health Organization classification of epithelial digestive tumours |
| Abstract: | Molecular biomarkers have come to constitute one of the cornerstones of oncological pathology. The method of classification not only directly affects the manner in which patients are diagnosed and treated, but also guides the development of drugs and of artificial intelligence tools. The aim of this article is to organise and update gastrointestinal molecular biomarkers in order to produce an easy-to-use guide for routine diagnostics. For this purpose, we have extracted and reorganised the molecular information on epithelial neoplasms included in the 2019 World Health Organization classification of tumours. Digestive system tumours, 5th edn. © 2020 The Authors. Histopathology published by John Wiley & Sons Ltd |
| Keywords: | review; biomarkers; tumor marker; gastrointestinal neoplasms; molecular marker; diagnostic value; colon tumor; genomics; rectum tumor; tumor classification; epithelium tumor; tumor diagnosis; esophagus tumor; digestive system tumor; stomach tumor; appendix tumor; molecular pathology; molecular diagnosis; anus tumor; who; small intestine tumor; human; priority journal; gastrointestinal tissue |
| Journal Title: | Histopathology |
| Volume: | 77 |
| Issue: | 3 |
| ISSN: | 0309-0167 |
| Publisher: | Wiley Blackwell |
| Date Published: | 2020-09-01 |
| Start Page: | 340 |
| End Page: | 350 |
| Language: | English |
| DOI: | 10.1111/his.14120 |
| PUBMED: | 32320495 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Export Date: 1 October 2020 -- Source: Scopus |
