Intraparenchymal brain metastases: MR imaging versus contrast-enhanced CT Journal Article


Authors: Sze, G.; Shin, J.; Krol, G.; Johnson, C.; Liu, D.; Deck, M. D. F.
Article Title: Intraparenchymal brain metastases: MR imaging versus contrast-enhanced CT
Abstract: Prospective and retrospective studies of 75 patients were performed to assess the sensitivities of magnetic resonance (MR) imaging and computed tomography (CT) in the evaluation of suspected intraparenchymal brain metastases. The findings on MR images were equivalent to those on CT scans in 49 of the 75 patients; the remaining findings were discordant in 26 patients, and neither MR imaging nor CT was consistently superior. MR imaging demonstrated more metastases in nine of these 26 patients. However, contrast material-enhanced CT scans were superior in cesion depiction in eight of the 26 patients. Large enhanced lesions that were nearly isointense on MR images were seen well on CT scans. In several cases in which results were discordant, gadolinium-diethylenetriaminepentaacetic acid (DTPA)-enhanced MR images were obtained, and this agent behaved similarly to iodinated contrast agents. If indicated clinically, such as before surgery for a single metastasis, the authors perform both MR imaging and contrast-enhanced CT. Gd-DTPA-enhanced MR imaging may prove to be the method of choice for depiction of intraparenchymal metastases.
Keywords: adolescent; adult; child; major clinical study; comparative study; nuclear magnetic resonance imaging; methodology; computer assisted tomography; infant; brain metastasis; gadolinium pentetate; intravenous drug administration; computer analysis; diatrizoate; meglumine diatrizoate; human; male; female
Journal Title: Radiology
Volume: 168
Issue: 1
ISSN: 0033-8419
Publisher: Radiological Society of North America, Inc.  
Date Published: 1988-07-01
Start Page: 187
End Page: 194
Language: English
DOI: 10.1148/radiology.168.1.3380956
PUBMED: 3380956
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 6 August 2020 -- Source: Scopus
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  1. George Krol
    86 Krol
  2. Michael D F Deck
    13 Deck
  3. Gordon Sze
    36 Sze