Malignant extradural spinal tumors: MR imaging with Gd-DTPA Journal Article
| Authors: | Sze, G.; Krol, G.; Zimmerman, R. D.; Deck, M. D. F. |
| Article Title: | Malignant extradural spinal tumors: MR imaging with Gd-DTPA |
| Abstract: | Magnetic resonance (MR) imaging with gadolinium diethylenetriaminepentaacetic acid (DTPA) was performed in 12 patients with neoplasia of the spine and epidural space. Postcontrast images were compared with precontrast images. Gd-DTPA MR images did not improve the detection of tumors affecting the epidural space of the spine. In fact, many lesions were isointense when compared with the intensity of the surrounding bone marrow and were difficult to see. Because of this, contrast material-enhanced images were not sufficient; however, when they were combined with precontrast images, the use of Gd-DTPA improved the delineation and characterization of certain lesions. Gd-DTPA MR images were helpful in differentiating disk herniation from epidural tumors, indicating regions of more active tumor for biopsy, outlining areas of spinal cord compression, and demonstrating tumor response to therapy. Therefore, while it may be unlikely that Gd-DTPA will be used routinely in every case of suspected neoplasia of the epidural space, contrast-enhanced images will undoubtedly have an adjunctive role in certain clinical applications. |
| Keywords: | adult; aged; nuclear magnetic resonance imaging; metastasis; multiple myeloma; ewing sarcoma; spinal cord compression; lymphoma; gadolinium pentetate; intravenous drug administration; computer analysis; spine cancer; human; male; female |
| Journal Title: | Radiology |
| Volume: | 167 |
| Issue: | 1 |
| ISSN: | 0033-8419 |
| Publisher: | Radiological Society of North America, Inc. |
| Date Published: | 1988-04-01 |
| Start Page: | 217 |
| End Page: | 223 |
| Language: | English |
| DOI: | 10.1148/radiology.167.1.3347725 |
| PUBMED: | 3347725 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 6 August 2020 -- Source: Scopus; Acknowledgements: We thank Patricia Dudley for help in manuscript preparation, and Nicole Baccon, B. A., Noreen O'Donnell, B. S., and Bruce Peters, B. S., for technologic assistance. |
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