Abstract: |
Cancer of the laryngopharynx can be a devastatingly aggressive and fatal disease. Prognosis is directly related to the extent of the tumor when treated. Every attempt should be made to detect and effectively treat cancers when they are early. More advanced tumors carry a more grave prognosis, regardless of treatment, demand more radical and extensive resections, and require postoperative radiation therapy if maximum local-regional control is to be achieved. Quality of life may be enhanced by conservation surgery when extent of disease permits and the patient is a suitable candidate. Immediate reconstruction is preferred over delayed procedures. Prevention of further head and neck and related cancers can be enhanced by convincing patients to stop tobacco and alcohol abuse. The role of chemotherapy in the routine management of cancers of the laryngopharynx remains to be defined. Whereas combined surgical and radiation therapy may enhance local-regional control, other factors, particularly the propensity to distant metastases, may minimize any improvement in long-term survival rates. |