Surgical implications of hepatic venocclusive disease following bone marrow transplantation Journal Article

  


Authors: Gottesman, L.; Turnbull, A. D.; O'Reilly, R. J.
Article Title: Surgical implications of hepatic venocclusive disease following bone marrow transplantation
Abstract: Hepatic venocclusive disease occurs with a spectrum of severity in an estimated 21% of bone marrow transplant patients. Clinical features include severe right upper quadrant pain, ascites, weight gain and initially minimal derangement of liver function. In contrast to hepatic graft versus host disease, venocclusive disease usually occurs within the first three weeks of engraftment and in autologous grafts. Urgent surgical consultation is requested when these features are prominent enough to mimic common acute processes requiring laparotomy. This condition must be included in the differential diagnosis in order to avoid an unnecessary laparotomy in this select group of patients who are usually severely thrombocytopenic and leukopenic. Clinical diagnosis alone is very reliable. Copyright © 1988 Wiley‐Liss, Inc., A Wiley Company
Keywords: leukemia; case report; ascites; cytarabine; bone marrow; etoposide; cyclophosphamide; dexamethasone; vincristine; lomustine; liver failure; daunorubicin; bone marrow transplantation; tioguanine; human; female; priority journal; venocclusive
Journal Title: Journal of Surgical Oncology
Volume: 37
Issue: 2
ISSN: 0022-4790
Publisher: Wiley Blackwell  
Date Published: 1988-02-01
Start Page: 113
End Page: 115
Language: English
DOI: 10.1002/jso.2930370210
PUBMED: 3278166
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023831132&doi=10.1002%2fjso.2930370210&partnerID=40&md5=83307bb2fcf40021656c3b14ed3e23dc
Notes: Article -- Export Date: 6 August 2020 -- Source: Scopus
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MSK Authors
  1. Alan Turnbull
    42 Turnbull
  2. Richard O'Reilly
    747 O'Reilly
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