Comparison of Roche RIA, Roche EIA, Hybritech EIA, and Abbott EIA methods for measuring carcinoembryonic antigen Journal Article
| Authors: | Nisselbaum, J. S.; Smith, C. A.; Schwartz, D.; Schwartz, M. K. |
| Article Title: | Comparison of Roche RIA, Roche EIA, Hybritech EIA, and Abbott EIA methods for measuring carcinoembryonic antigen |
| Abstract: | Using 600 clinical specimens, we compared the concordance of four methods for carcinoembryonic antigen: the Roche RIA (I); the Roche EIA (II); Hybritech EIA (III); and Abbott EIA (IV). EDTA-treated plasma was used for Methods I and II and serum for Methods III and IV. However, no significant difference was found between results for serum and plasma in Method II. The normal reference interval (in μg/L) was I (222 specimens), 1.94 ± 1.54; II (57 specimens), 0.8 ± 0.5; III (100 specimens), 2.94 ± 2.47; and IV (614 specimens), <5.0. The precision of all four methods was acceptable. Concordance among all of the methods exceeded 90%. |
| Keywords: | human cell; major clinical study; carcinoembryonic antigen; enzyme immunoassay; radioisotope; plasma; radioimmunoassay; male; female |
| Journal Title: | Clinical Chemistry |
| Volume: | 34 |
| Issue: | 4 |
| ISSN: | 0009-9147 |
| Publisher: | American Association for Clinical Chemistry |
| Date Published: | 1988-04-01 |
| Start Page: | 761 |
| End Page: | 764 |
| Language: | English |
| DOI: | 10.1093/clinchem/34.4.761 |
| PUBMED: | 3282721 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 6 August 2020 -- Source: Scopus |
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