Leukemic relapse presenting as sciatic nerve involvement by chloroma (granulocytic sarcoma) Journal Article


Authors: Stillman, M. J.; Christensen, W.; Payne, R.; Foley, K. M.
Article Title: Leukemic relapse presenting as sciatic nerve involvement by chloroma (granulocytic sarcoma)
Abstract: A relapse of acute nonlymphocytic leukemia in a child presented as subacute mononeuropathy involving the sciatic nerve. Surgical exploration showed a chloroma (granulocytic sarcoma) of the distal sciatic nerve, but resection and irradiation did not lead to recovery of nerve function or complete resolution of the patient's symptomatic neuropathic pain. This case represents a rare neurologic complication of what is currently an uncommon presentation for leukemic relapse, and may be the only reported case of chloromatous involvement of the peripheral nervous system (PNS) without coexisting epidural or leptomeningeal leukemia. Copyright © 1988 American Cancer Society
Keywords: child; case report; recurrence; acute leukemia; leukemia, myeloid; peripheral nervous system neoplasms; sciatic nerve; chloroma; leukemia, nonlymphocytic, acute; human; male; priority journal
Journal Title: Cancer
Volume: 62
Issue: 9
ISSN: 0008-543X
Publisher: Wiley Blackwell  
Date Published: 1988-11-01
Start Page: 2047
End Page: 2050
Language: English
DOI: 10.1002/1097-0142(19881101)62:9<2047::Aid-cncr2820620929>3.0.Co;2-w
PUBMED: 3167817
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 6 August 2020 -- Source: Scopus
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  1. Richard Payne
    68 Payne
  2. Kathleen M Foley
    199 Foley