Functional status and survival in patients ≥85 years of age who have keratinocyte carcinoma: A retrospective cohort study Journal Article

   

Authors:	Vora, N. B.; Connolly, K. L.; Dusza, S.; Rossi, A. M.; Nehal, K. S.; Lee, E. H.
Article Title:	Functional status and survival in patients ≥85 years of age who have keratinocyte carcinoma: A retrospective cohort study
Abstract:	Background: Functional status assessment may help estimate which patients ≥85 years of age will benefit from surgical treatment for keratinocyte carcinoma (KC), but predictive value for short-term survival in this population has not been determined. Objective: We sought to assess the predictive value of functional status for short-term survival in patients ≥85 years of age who have KC. Methods: This was a retrospective cohort review of 238 patients ≥85 years of age who presented for the management of KC between 2010 and 2015. Functional status was assessed with the Karnofsky Performance Scale (KPS) and Katz Activities of Daily Living (ADL) index. Overall survival was determined. Results: Lower functional status scores of KPS ≤40 and Katz ADL ≤4 were associated with 37% and 53% survival at 2 years, respectively. Limitations: Retrospective design and single-center study. Conclusion: In this study, KPS and Katz ADL predicted short-term survival. Patients with low functional status scores had significantly decreased survival at 2 years, with double the death rate of patients with high functional status. Functional status should be considered during shared decision-making for elderly individuals who are seeking treatment for KC. © 2020 American Academy of Dermatology, Inc.
Keywords:	cancer survival; aged; survival analysis; cancer surgery; functional assessment; survival rate; major clinical study; overall survival; cancer patient; cancer radiotherapy; cohort analysis; medical record review; oncology; retrospective study; skin carcinoma; age; karnofsky performance status; conservative treatment; photodynamic therapy; geriatric patient; functional status; topical treatment; mohs micrographic surgery; predictive value; curettage; geriatrics; cryotherapy; karnofsky performance scale; cancer prognosis; very elderly; human; male; female; priority journal; article; electrodessication; keratinocyte carcinoma; topical agent; katz adl; katz index; short term survival
Journal Title:	Journal of the American Academy of Dermatology
Volume:	83
Issue:	2
ISSN:	0190-9622
Publisher:	Mosby Elsevier
Date Published:	2020-08-01
Start Page:	463
End Page:	468
Language:	English
DOI:	10.1016/j.jaad.2020.04.042
PUBMED:	32320764
PROVIDER:	scopus
PMCID:	PMC7377923
DOI/URL:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85086337604&doi=10.1016%2fj.jaad.2020.04.042&partnerID=40&md5=fe2ac4d4a090a045d75fb5cc6b291286
Notes:	Article -- Export Date: 1 September 2020 -- Source: Scopus

https://synapse.mskcc.org/synapse/works/has_related_data_chk/169984