Knowledge gaps in oncoplastic breast surgery Review

Authors: Weber, W. P.; Morrow, M.; Boniface, J. D.; Pusic, A.; Montagna, G.; Kappos, E. A.; Ritter, M.; Haug, M.; Kurzeder, C.; Saccilotto, R.; Schulz, A.; Benson, J.; Fitzal, F.; Matrai, Z.; Shaw, J.; Peeters, M. J. V.; Potter, S.; Heil, J.; on behalf of the Oncoplastic Breast Consortium
Review Title: Knowledge gaps in oncoplastic breast surgery
Abstract: The aims of the Oncoplastic Breast Consortium initiative were to identify important knowledge gaps in the field of oncoplastic breast-conserving surgery and nipple-sparing or skin-sparing mastectomy with immediate breast reconstruction, and to recommend appropriate research strategies to address these gaps. A total of 212 surgeons and 26 patient advocates from 55 countries prioritised the 15 most important knowledge gaps from a list of 38 in two electronic Delphi rounds. An interdisciplinary panel of the Oncoplastic Breast Consortium consisting of 63 stakeholders from 20 countries obtained consensus during an in-person meeting to select seven of these 15 knowledge gaps as research priorities. Three key recommendations emerged from the meeting. First, the effect of oncoplastic breast-conserving surgery on quality of life and the optimal type and timing of reconstruction after nipple-sparing or skin-sparing mastectomy with planned radiotherapy should be addressed by prospective cohort studies at an international level. Second, the role of adjunctive mesh and the positioning of implants during implant-based breast reconstruction should ideally be investigated by randomised controlled trials of pragmatic design. Finally, the BREAST-Q questionnaire is a suitable tool to assess primary outcomes in these studies, but other metrics to measure patient-reported outcomes should be systematically evaluated and quality indicators of surgical morbidity should be further assessed. © 2020 Elsevier Ltd
Keywords: breast neoplasms; breast reconstruction; mammaplasty; breast tumor; humans; human; female
Journal Title: Lancet Oncology
Volume: 21
Issue: 8
ISSN: 1470-2045
Publisher: Elsevier Science, Inc.  
Date Published: 2020-08-01
Start Page: e375
End Page: e385
Language: English
DOI: 10.1016/s1470-2045(20)30084-x
PUBMED: 32758475
PROVIDER: scopus
Notes: Review -- Export Date: 1 September 2020 -- Source: Scopus
Citation Impact
MSK Authors
  1. Monica Morrow
    702 Morrow