Knowledge gaps in oncoplastic breast surgery Review
| Authors: | Weber, W. P.; Morrow, M.; Boniface, J. D.; Pusic, A.; Montagna, G.; Kappos, E. A.; Ritter, M.; Haug, M.; Kurzeder, C.; Saccilotto, R.; Schulz, A.; Benson, J.; Fitzal, F.; Matrai, Z.; Shaw, J.; Peeters, M. J. V.; Potter, S.; Heil, J.; on behalf of the Oncoplastic Breast Consortium |
| Review Title: | Knowledge gaps in oncoplastic breast surgery |
| Abstract: | The aims of the Oncoplastic Breast Consortium initiative were to identify important knowledge gaps in the field of oncoplastic breast-conserving surgery and nipple-sparing or skin-sparing mastectomy with immediate breast reconstruction, and to recommend appropriate research strategies to address these gaps. A total of 212 surgeons and 26 patient advocates from 55 countries prioritised the 15 most important knowledge gaps from a list of 38 in two electronic Delphi rounds. An interdisciplinary panel of the Oncoplastic Breast Consortium consisting of 63 stakeholders from 20 countries obtained consensus during an in-person meeting to select seven of these 15 knowledge gaps as research priorities. Three key recommendations emerged from the meeting. First, the effect of oncoplastic breast-conserving surgery on quality of life and the optimal type and timing of reconstruction after nipple-sparing or skin-sparing mastectomy with planned radiotherapy should be addressed by prospective cohort studies at an international level. Second, the role of adjunctive mesh and the positioning of implants during implant-based breast reconstruction should ideally be investigated by randomised controlled trials of pragmatic design. Finally, the BREAST-Q questionnaire is a suitable tool to assess primary outcomes in these studies, but other metrics to measure patient-reported outcomes should be systematically evaluated and quality indicators of surgical morbidity should be further assessed. © 2020 Elsevier Ltd |
| Keywords: | breast neoplasms; breast reconstruction; mammaplasty; breast tumor; humans; human; female |
| Journal Title: | Lancet Oncology |
| Volume: | 21 |
| Issue: | 8 |
| ISSN: | 1470-2045 |
| Publisher: | Elsevier Science, Inc. |
| Date Published: | 2020-08-01 |
| Start Page: | e375 |
| End Page: | e385 |
| Language: | English |
| DOI: | 10.1016/s1470-2045(20)30084-x |
| PUBMED: | 32758475 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Export Date: 1 September 2020 -- Source: Scopus |
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