Burkitt lymphoma - Subtypes, pathogenesis, and treatment strategies Meeting Abstract
| Author: | Noy, A. |
| Abstract Title: | Burkitt lymphoma - Subtypes, pathogenesis, and treatment strategies |
| Meeting Title: | 8th Annual Meeting of the Society of Hematologic Oncology (SOHO) |
| Abstract: | Burkitt's lymphoma (BL) is a rare and highly aggressive Non-Hodgkin lymphoma (NHL) with a germinal center phenotype, a nearly universal myc oncogene translocation to an enhancer element and a proliferation index greater than 95%.1 Bcl-2 is not expressed as opposed to double-hit or triple-hit lymphoma. Genetic mutations and aberrancy involving the phosphatidylcholine 3-kinase and cyclin-dependent kinase pathways are also involved.2–5 Rarely patients present with stage I disease and others are considered as high risk if greater than stage I or with elevated LDH or masses greater than 10 cm. © 2020 Elsevier Inc. |
| Keywords: | burkitt lymphoma; aggressive; bl |
| Journal Title: | Clinical Lymphoma, Myeloma and Leukemia |
| Volume: | 20 |
| Issue: | Suppl. 1 |
| Meeting Dates: | 2020 Sep 9-12 |
| Meeting Location: | Houston, TX |
| ISSN: | 2152-2650 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2020-09-01 |
| Start Page: | S37 |
| End Page: | S38 |
| Language: | English |
| DOI: | 10.1016/s2152-2650(20)30455-9 |
| PROVIDER: | scopus |
| PUBMED: | 32862862 |
| DOI/URL: | |
| Notes: | Due to Covid-19 pandemic the conference was held virtually -- Export Date: 1 September 2020 -- Source: Scopus |
