Management of thymoma-associated pure red cell aplasia: A novel use of blood substitute HBOC-201 in a Jehovah’s Witness Journal Article

   


Authors: Rubinstein, M. M.; Goss, C.; Avecilla, S. T.; Dubé, G. P.; Riely, G. J.; Mones, J. V.
Article Title: Management of thymoma-associated pure red cell aplasia: A novel use of blood substitute HBOC-201 in a Jehovah’s Witness
Abstract: Pure red cell aplasia (PRCA) is a rare paraneoplastic syndrome occasionally associated with thymomas. Here, we report on the first ever use of a bovine hemoglobin-based oxygen carrier, HBOC-201 (HbO2 Therapeutics LLC; Hemopure®, Waltham, MA) for the supportive management of pure red cell aplasia in a Jehovah Witness patient. © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.
Keywords: adult; clinical article; middle aged; prednisone; case report; methylene blue; erythropoietin; erythropoiesis; hemolysis; nausea; vomiting; hemoglobin; abdominal pain; pneumonia; hypoxia; dysphagia; hypotension; ischemia; iron; ascorbic acid; folic acid; headache; enterococcus; echocardiography; immunosuppressive treatment; paraneoplastic syndrome; thymoma; atrial fibrillation; abdominal cramp; cyclosporine; reticulocyte count; cyanocobalamin; piperacillin plus tazobactam; hematocrit; cardiopulmonary arrest; phenylephrine; klebsiella; methemoglobinemia; pure red cell anemia; methemoglobin; human; female; priority journal; article; heart right ventricle hypertrophy; pure red cell aplasia; blood substitute; jehovah's witness; hemoglobin-based oxygen carrier; hemopure; red blood cell alternatives; polymerized hemoglobin; reticulocyte hemoglobin content
Journal Title: Clinical Case Reports
Volume: 8
Issue: 2
ISSN: 2050-0904
Publisher: Wiley Blackwell  
Date Published: 2020-02-01
Start Page: 289
End Page: 292
Language: English
DOI: 10.1002/ccr3.2626
PROVIDER: scopus
PMCID: PMC7044386
PUBMED: 32128175
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85077358966&doi=10.1002%2fccr3.2626&partnerID=40&md5=84b34de2f3d6f691e2d25cebb9201fae
Notes: Article -- Export Date: 3 August 2020 -- Source: Scopus
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MSK Authors
  1. Gregory J Riely
    599 Riely
  2. Maria Michelle Rubinstein
    35 Zlobinsky
  3. Scott Terence Avecilla
    69 Avecilla
  4. Cheryl Goss
    17 Goss
  5. Jodi Victoria Mones
    20 Mones
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