Authors: | Causa Andrieu, P. I.; Golia Pernicka, J. S.; Faria e Silva Costa, G.; Chesnut, G. T.; Shandu, J. S.; Ying-Bei, C.; Petkovska, I. |
Article Title: | Isolated urethral metastasis from appendiceal mucinous adenocarcinoma |
Abstract: | We are presenting a compelling case of a 61-year-old female with a history of appendiceal mucinous adenocarcinoma (AMA) with a new complaint of irritative lower urinary tract symptoms. Magnetic resonance imaging (MRI) showed a semi-circumferential, T2 hyperintense, rim enhancing, and lacking restricted diffusion lesion involving the urethra and infiltrating the right perineal and internal obturator muscles. The suspected differential diagnosis was urethral malignancy, based on her cancer history and MRI findings. After interdisciplinary consensus, the patient underwent excision of the lesion, and pathology was consistent with metastasis from the primary tumor. The urethra is a rare site of primary malignancy and metastatic disease. In particular, a non-contiguous metastatic disease involving the urethra is exceedingly rare. To the best of our knowledge, this is the first report of an AMA metastasizing to the urethra. © 2020 Elsevier Inc. |
Keywords: | adult; clinical article; disease course; cancer recurrence; case report; bevacizumab; fluorouracil; nuclear magnetic resonance imaging; magnetic resonance imaging; laparoscopy; tumor localization; metastasis; differential diagnosis; palliative therapy; adenocarcinoma, mucinous; vagina disease; pathology; carcinogenesis; irinotecan; lung metastasis; folinic acid; diagnosis; urinary frequency; disease duration; urinary urgency; colloid carcinoma; diffusion weighted imaging; small intestine obstruction; dysuria; metastatic disease; urethra carcinoma; appendix tumor; peritoneal disease; appendiceal neoplasms; medical history; urethral neoplasms; restricted diffusion; nocturia; pubic bone; lower urinary tract symptoms; human; female; priority journal; article; urethral metastasis |
Journal Title: | Clinical Imaging |
Volume: | 67 |
ISSN: | 0899-7071 |
Publisher: | Elsevier Inc. |
Date Published: | 2020-11-01 |
Start Page: | 68 |
End Page: | 71 |
Language: | English |
DOI: | 10.1016/j.clinimag.2020.05.030 |
PUBMED: | 32526660 |
PROVIDER: | scopus |
PMCID: | PMC8207824 |
DOI/URL: | |
Notes: | Article -- Jaspreet Sandhu's name appears to be misspelled in the author list as Jaspreet S. Shandu; Yingbei Chen's name is listed as Chen Ying-Bei in the author list -- Export Date: 1 July 2020 -- Source: Scopus |