Polypoid endometriosis: A mimic of malignancy Journal Article


Authors: Ghafoor, S.; Lakhman, Y.; Park, K. J.; Petkovska, I.
Article Title: Polypoid endometriosis: A mimic of malignancy
Abstract: This an interesting case of an asymptomatic 60-year-old postmenopausal patient with an incidental pelvic mass mimicking a pelvic malignancy on imaging. Biopsy revealed findings consistent with polypoid endometriosis. After discontinuation of hormone replacement therapy, the mass showed decrease in size on follow-up imaging. Polypoid endometriosis is a rare but distinct variant of endometriosis with histopathologic features akin to an endometrial polyp. Clinical and imaging features of polypoid endometriosis differ from classic endometriosis. While classic endometriosis predominates in premenopausal women, polypoid endometriosis more commonly affects peri- to postmenopausal women and is associated with the exposure to Tamoxifen or hormone replacement therapy. Imaging features that aid in the diagnosis of polypoid endometriosis are a T2 hyperintense polypoid mass with signal characteristics similar to endometrium, a T2 hypointense peripheral rim, contrast enhancement pattern mirroring the enhancement of the endometrium, and lack of diffusion restriction. Radiologists should be familiar with polypoid endometriosis because this clinically and morphologically distinct variant may mimic malignant neoplasms on imaging. © 2019, Springer Science+Business Media, LLC, part of Springer Nature.
Keywords: adult; clinical article; human tissue; middle aged; clinical feature; histopathology; case report; drug withdrawal; nuclear magnetic resonance imaging; follow up; pelvis; image subtraction; contrast enhancement; fluorodeoxyglucose f 18; tamoxifen; postmenopause; sigmoidoscopy; endometrium biopsy; hormone substitution; endometriosis; polypoid endometriosis; endometrium polyp; human; female; priority journal; article; positron emission tomography-computed tomography; endometriosis-associated malignancy; magnetic resonance imaging/mri
Journal Title: Abdominal Radiology
Volume: 45
Issue: 6
ISSN: 2366-004X
Publisher: Springer  
Date Published: 2020-06-01
Start Page: 1776
End Page: 1782
Language: English
DOI: 10.1007/s00261-019-02143-8
PUBMED: 31372776
PROVIDER: scopus
PMCID: PMC8293290
DOI/URL:
Notes: Article -- Source: Scopus
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  1. Yuliya Lakhman
    95 Lakhman
  2. Kay Jung Park
    305 Park
  3. Soleen Ghafoor
    17 Ghafoor