Diet and the risk of head and neck cancer: A pooled analysis in the INHANCE consortium Journal Article
| Authors: | Chuang, S. C.; Jenab, M.; Heck, J. E.; Bosetti, C.; Talamini, R.; Matsuo, K.; Castellsague, X.; Franceschi, S.; Herrero, R.; Winn, D. M.; Vecchia, C. L.; Morgenstern, H.; Zhang, Z. F.; Levi, F.; Maso, L. D.; Kelsey, K.; McClean, M. D.; Vaughan, T.; Lazarus, P.; Muscat, J.; Ramroth, H.; Chen, C.; Schwartz, S. M.; Eluf-Neto, J.; Hayes, R. B.; Purdue, M.; Boccia, S.; Cadoni, G.; Zaridze, D.; Koifman, S.; Curado, M. P.; Ahrens, W.; Benhamou, S.; Matos, E.; Lagiou, P.; Szeszenia-Dabrowska, N.; Olshan, A. F.; Fernandez, L.; Menezes, A.; Agudo, A.; Daudt, A. W.; Merletti, F.; MacFarlane, G. J.; Kjaerheim, K.; Mates, D.; Holcatova, I.; Schantz, S.; Yu, G. P.; Simonato, L.; Brenner, H.; Mueller, H.; Conway, D. I.; Thomson, P.; Fabianova, E.; Znaor, A.; Rudnai, P.; Healy, C. M.; Ferro, G.; Brennan, P.; Boffetta, P.; Hashibe, M. |
| Article Title: | Diet and the risk of head and neck cancer: A pooled analysis in the INHANCE consortium |
| Abstract: | We investigated the association between diet and head and neck cancer (HNC) risk using data from the International Head and Neck Cancer Epidemiology (INHANCE) consortium. The INHANCE pooled data included 22 case-control studies with 14,520 cases and 22,737 controls. Center-specific quartiles among the controls were used for food groups, and frequencies per week were used for single food items. A dietary pattern score combining high fruit and vegetable intake and low red meat intake was created. Odds ratios (OR) and 95% confidence intervals (CI) for the dietary items on the risk of HNC were estimated with a two-stage random-effects logistic regression model. An inverse association was observed for higher-frequency intake of fruit (4th vs. 1st quartile OR = 0.52, 95% CI = 0.43-0.62, p trend < 0.01) and vegetables (OR = 0.66, 95% CI = 0.49-0.90, p trend = 0.01). Intake of red meat (OR = 1.40, 95% CI = 1.13-1.74, p trend = 0.13) and processed meat (OR = 1.37, 95% CI = 1.14-1.65, p trend < 0.01) was positively associated with HNC risk. Higher dietary pattern scores, reflecting high fruit/vegetable and low red meat intake, were associated with reduced HNC risk (per score increment OR = 0.90, 95% CI = 0.84-0.97). © 2011 Springer Science+Business Media B.V. |
| Keywords: | adult; controlled study; aged; major clinical study; case control study; cancer risk; disease association; risk factor; risk assessment; diet; head and neck cancer; fruit; vegetable; dietary intake; logistic regression analysis; red meat; fruit and vegetable; processed meat; food processing |
| Journal Title: | Cancer Causes & Control |
| Volume: | 23 |
| Issue: | 1 |
| ISSN: | 0957-5243 |
| Publisher: | Springer |
| Date Published: | 2012-01-01 |
| Start Page: | 69 |
| End Page: | 88 |
| Language: | English |
| DOI: | 10.1007/s10552-011-9857-x |
| PROVIDER: | scopus |
| PUBMED: | 22037906 |
| PMCID: | PMC3654401 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 3 January 2012" - "CODEN: CCCNE" - "Source: Scopus" |
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