An efficient copper-catalyzed microwave-assisted S-arylation towards the synthesis of 8-arylsulfanyl adenines Journal Article
| Authors: | Sun, W.; Patel, P. D.; Stephani, R. A.; Chiosis, G. |
| Article Title: | An efficient copper-catalyzed microwave-assisted S-arylation towards the synthesis of 8-arylsulfanyl adenines |
| Abstract: | We report a microwave-assisted synthetic protocol for the C-S cross-coupling reaction of aryl iodides and 8-mercaptoadenine using CuI and n-Bu4NBr with NaOt-Bu in DMF. The method is rapid, simple, and cost efficient, and leads in high yields to biologically relevant aryl sulfides. © Georg Thieme Verlag Stuttgart · New York. |
| Keywords: | copper-catalyzed s-arylation; microwave; phase-transfer catalyst |
| Journal Title: | Synlett |
| Volume: | 2011 |
| Issue: | 20 |
| ISSN: | 0936-5214 |
| Publisher: | Georg Thieme Verlag Kg |
| Date Published: | 2011-01-01 |
| Start Page: | 3008 |
| End Page: | 3012 |
| Language: | English |
| DOI: | 10.1055/s-0031-1289888 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Export Date: 3 January 2012" - "Art. No.: S04711ST" - "CODEN: SYNLE" - "Source: Scopus" |
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