Detection of bladder carcinoma in females by flow cytometry and cytology Journal Article

  


Authors: Hermansen, D. K.; Badalament, R. A.; Fair, W. R.; Kimmel, M.; Whitmore, W. F. Jr; Melamed, M. R.
Article Title: Detection of bladder carcinoma in females by flow cytometry and cytology
Abstract: The sensitivity of bladder wash flow cytometry (BWFCM), voided urinary cytology (VUC), and cytology of cathetrized urine obtained at the time of cystoscopy (CUC) were reviewed on all women evaluated for bladder cancer at Memorial Sloan‐Kettering Cancer Center between June 1985 and December 1986. This comprised sixty‐four episodes of pathologically proven bladder cancer in 48 women. Considering positive and suspicious results jointly the sensitivities of BWFCM, CUC and 3 VUC were 75%, 64% and 56%, respectively. If only positive results were considered (i.e., suspicious results considered as negative), the sensitivities of BWFCM, CUC and 3 VUC were 64%, 31% and 32%, respectively. The sensitivities of these tests are less than for a predominantly male population, presumably related to the presence of squamous epithelium and greater frequency of pyuria. However, bladder wash flow cytometry and conventional cytology are still a very valuable addition to cystoscopic examination, and the combination of BWFCM with conventional cytology is more sensitive than either procedure alone. Copyright © 1989 Wiley‐Liss, Inc.
Keywords: adult; clinical article; aged; aged, 80 and over; comparative study; flow cytometry; methodology; carcinoma, papillary; bladder cancer; biopsy; carcinoma in situ; dna, neoplasm; bladder neoplasms; cystoscopy; cytochemistry; middle age; human; female; priority journal; article; support, u.s. gov't, p.h.s.; bladder wash flow cytometry; voided urinary cytology
Journal Title: Cytometry
Volume: 10
Issue: 6
ISSN: 0196-4763
Publisher: Wiley Liss  
Date Published: 1989-11-01
Start Page: 739
End Page: 742
Language: English
DOI: 10.1002/cyto.990100611
PUBMED: 2582965
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024355948&doi=10.1002%2fcyto.990100611&partnerID=40&md5=6040f76047616caa032deda922079cc3
Notes: Article -- Export Date: 14 April 2020 -- Source: Scopus
Altmetric
What is Altmetric?
Citation Impact
What is Dimensions Citation Badge?
BMJ Impact Analytics
MSK Authors
  1. William R Fair
    342 Fair
  2. Willet F. Whitmore Jr
    139 Whitmore
  3. Myron Melamed
    148 Melamed
  4. Marek Kimmel
    46 Kimmel
  5. Robert A. Badalament
    16 Badalament
Related MSK Work