The clinical significance of vascular invasion in colorectal cancer Journal Article
| Authors: | Minsky, B.; Mies, C. |
| Article Title: | The clinical significance of vascular invasion in colorectal cancer |
| Abstract: | A number of investigators have examined the influence of vascular invasion by tumor in colon, rectal, and colorectal cancer. Some consider the presence of vascular invasion an unfavorable prognostic feature and propose treatment recommendations based on its presence. Vascular invasion has two distinct components: blood vessel invasion and lymphatic vessel invasion. The use of elastic tissue stains enhance both the detection of blood vessel invasion and its differentiation from lymphatic vessel invasion. Almost all series report an increased incidence of blood vessel invasion with increasing stage and grade. Although the influence of blood vessel invasion and lymphatic vessel invasion on patterns of failure is variable, both are associated with a decrease in survival; however, treatment recommendations based solely on the presence of blood vessel invasion or lymphatic vessel invasion should be made with caution. © 1989 American Society of Colon and Rectal Surgeons. |
| Keywords: | lymphatic metastasis; colorectal cancer; colorectal neoplasms; lymph vessel; short survey; neoplasm invasiveness; staining and labeling; elastic tissue; vascular invasion; vascular diseases; prognosis; human; priority journal; blood vessel invasion; lymphatic vessel invasion |
| Journal Title: | Diseases of the Colon and Rectum |
| Volume: | 32 |
| Issue: | 9 |
| ISSN: | 0012-3706 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 1989-09-01 |
| Start Page: | 794 |
| End Page: | 803 |
| Language: | English |
| DOI: | 10.1007/bf02562132 |
| PUBMED: | 2474414 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 14 April 2020 -- Source: Scopus |
Altmetric
Citation Impact
BMJ Impact Analytics
Related MSK Work