New intraoperative brachytherapy techniques for positive or close surgical margins Journal Article


Authors: Nori, D.; Bains, M.; Hilaris, B. S.; Harrison, L.; Fass, D.; Peretz, T.; Donath, D.; Fuks, Z.
Article Title: New intraoperative brachytherapy techniques for positive or close surgical margins
Abstract: Tumors attached or adjacent to critical structures can often not be completely resected or resected with adequate surgical margins. Sites involving major blood vessels, the paravertebral spaces, or critical abdominal structures often present technical difficulties for standard brachytherapy procedures using 1‐125 or Ir‐192 implants. These techniques allow for a high‐dose delivery to the tumor bed with minimal normal tissue toxicity. A relatively simple and accurate method is described using 1‐125 seeds in Vicryl® suture threaded through Gelfoam®. These permanent implant procedures with radioactive 1‐125 seeds effectively treat small residual tumors or suspicious margins where standard brachytherapy techniques may be unsatisfactory and technically difficult to perform. Copyright © 1989 Wiley‐Liss, Inc., A Wiley Company
Keywords: human cell; methodology; metastasis; brachytherapy; radioisotope; radionuclide; suture; human; priority journal; 1‐125 implant; 1‐125 intraoperative plaque
Journal Title: Journal of Surgical Oncology
Volume: 42
Issue: 1
ISSN: 0022-4790
Publisher: Wiley Blackwell  
Date Published: 1989-09-01
Start Page: 54
End Page: 59
Language: English
DOI: 10.1002/jso.2930420112
PUBMED: 2770310
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 14 April 2020 -- Source: Scopus
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MSK Authors
  1. Zvi Fuks
    427 Fuks
  2. Manjit S Bains
    338 Bains
  3. Louis B Harrison
    123 Harrison
  4. Daniel E. Fass
    29 Fass
  5. Dattatreyudu Nori
    38 Nori