Mechanisms of clinical pain: Observations and speculations Journal Article
| Author: | Portenoy, R. K. |
| Article Title: | Mechanisms of clinical pain: Observations and speculations |
| Abstract: | Advances in basic research have provided extraordinary insights into the physiologic systems subserving pain transmission and modulation. Although these data can provide a foundation for the understanding of clinical pain, the relationship between clinical phenomena and the diverse findings of studies performed in animal and human models of experimental pain is often obscure. A classification of pain pathophysiology is proposed in an effort to clarify this relationship. Within this classification, the data that elucidate the mechanisms of specific pain-related phenomena observed in the clinical setting are reviewed. |
| Keywords: | review; animal; pain; neuropathy; chronic disease; hyperalgesia; nociception; nervous system; deafferentation; human; referred pain; psychogenic pain |
| Journal Title: | Neurologic Clinics |
| Volume: | 7 |
| Issue: | 2 |
| ISSN: | 0733-8619 |
| Publisher: | W.B. Saunders Co-Elsevier Inc. |
| Date Published: | 1989-05-01 |
| Start Page: | 205 |
| End Page: | 230 |
| Language: | English |
| PUBMED: | 2657376 |
| PROVIDER: | scopus |
| DOI: | 10.1016/s0733-8619(18)30810-7 |
| DOI/URL: | |
| Notes: | Review in "Pain: Mechanisms and Syndromes" -- Export Date: 14 April 2020 -- Source: Scopus |
