Conservative management of invasive rectal cancer: Alternative to abdominoperineal resection Journal Article
| Authors: | Minsky, B. D.; Cohen, A. M. |
| Article Title: | Conservative management of invasive rectal cancer: Alternative to abdominoperineal resection |
| Abstract: | The standard treatment for patients with distal invasive rectal cancer who are unable to undergo a low anterior resection (LAR) is an abdominoperineal resection (APR). Although an APR offers excellent cure rates, it is associated with complications such as urological dysfunction, male impotence, and requires a permanent colostomy. Local excision alone is not adequate. If there is no evidence of gross disease in the pelvis, sphincter-sparing surgery (with negative margins) with adjuvant pelvic radiation therapy may be an alternative to abdominoperineal resection. Further follow-up will be needed to determine if this approach ultimately achieves local control and survival rates similar to an APR. |
| Keywords: | review; multimodality cancer therapy; postoperative care; preoperative care; combined modality therapy; methodology; lymph node metastasis; lymph nodes; lymphatic metastasis; radiotherapy; pathology; cancer invasion; abdomen; lymph node; neoplasm invasiveness; rectal neoplasms; rectum tumor; rectum; peritoneum; human; support, non-u.s. gov't |
| Journal Title: | Oncology (Norwalk) |
| Volume: | 3 |
| Issue: | 5 |
| ISSN: | 0890-9091 |
| Publisher: | C M P Medica LLC * The Oncology Group |
| Date Published: | 1989-05-01 |
| Start Page: | 137 |
| End Page: | 142; discussion 142, 146 |
| Language: | English |
| PUBMED: | 2577881 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Export Date: 14 April 2020 -- Source: Scopus |
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