Immediate vs. salvage resection after local treatment for early rectal cancer Journal Article

  


Authors: Baron, P. L.; Enker, W. E.; Zakowski, M. F.; Urmacher, C.
Article Title: Immediate vs. salvage resection after local treatment for early rectal cancer
Abstract: PURPOSE: There is an increasing awareness of local procedures to treat early stage rectal cancer. Abdominoperineal resection (APR) or low anterior resection (LAR) has been recommended if adverse pathologic findings are encountered in the local excision specimen. No data compare the impact on survival of "immediate" resection for adverse features vs. "salvage" resection for clinical recurrence. METHODS: We reviewed retrospectively 155 patients who underwent initial curative treatment of invasive rectal cancer by excision (91), snare-cautery (44), and fulguration (20). RESULTS: Twenty-one patients underwent APR/LAR immediately after initial local treatment, whereas another 21 patients underwent salvage APR/LAR for local recurrence. The disease-free survival after APR/LAR was 94.1 percent for the immediate group and 55.5 percent for the delayed group (P<0.05). CONCLUSION: This decreased survival observed after delayed resection supports the recommendation for immediate APR/LAR when adverse pathologic features are present in the excision specimen. © 1995 American Society of Colon and Rectal Surgeons.
Keywords: cancer survival; aged; disease-free survival; excision; survival rate; retrospective studies; major clinical study; salvage therapy; multimodality cancer therapy; patient selection; radiotherapy, adjuvant; follow-up studies; neoplasm staging; neoplasm recurrence, local; time factors; carcinoma; surgery; neoplasm invasiveness; rectal neoplasms; rectum cancer; transanal excision; rectum; colostomy; rectum abdominoperineal resection; cauterization; human; male; female; article
Journal Title: Diseases of the Colon and Rectum
Volume: 38
Issue: 2
ISSN: 0012-3706
Publisher: Lippincott Williams & Wilkins  
Date Published: 1995-02-01
Start Page: 177
End Page: 181
Language: English
DOI: 10.1007/bf02052447
PUBMED: 7851173
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028928625&doi=10.1007%2fBF02052447&partnerID=40&md5=e69ea18e55f0f4947e5174b684d064a1
Notes: Article -- Export Date: 28 August 2018 -- Source: Scopus
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MSK Authors
  1. Maureen F Zakowski
    289 Zakowski
  2. Warren E. Enker
    70 Enker
  3. Carlos D. Urmacher
    45 Urmacher
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